33432-53-0Relevant articles and documents
Reaction of 4-aryl-2-methylbut-3-yn-2-ols with thiourea as a new approach to the synthesis of 4-arylmethylidene-5,5-dimethyl-4,5-dihydrothiazole-2-amines
Baranov,Mamatyuk,Gatilov,Vasilevsky
, (2012)
A reaction of thiourea with 4-aryl-2-methylbut-3-yn-2-ols in refluxing pyridine led to the synthesis of 4-arylmethylidene-5,5-dimethyl-4,5- dihydrothiazole-2-amines.
Ru(ii)-catalyzed allenylation and sequential annulation of: N -tosylbenzamides with propargyl alcohols
Kumar, Shreemoyee,Nair, Akshay M.,Volla, Chandra M. R.
supporting information, p. 6280 - 6283 (2021/07/02)
We hereby report Ru(ii)-catalyzed C(sp2)-H allenylation of N-tosylbenzamides to access multi-substituted allenylamides. Furthermore, the allenylamides were converted to the corresponding isoquinolone derivatives via base mediated annulation. The current protocol features low catalyst loading, mild reaction conditions, high functional group compatibility and desired scalability. The unique functionality of the afforded allenes allowed further transformations to expand the practicality of the protocol. This journal is
Rip It off: Nitro to Nitroso Reduction by Iron Half-Sandwich Complexes
Korb, Marcus,Hosseini Ghazvini, Seyed Mohammad Bagher,Moggach, Stephen A.,Meunier, Jean-Fran?ois,Bousseksou, Azzedine,Low, Paul J.
supporting information, p. 4986 - 4995 (2021/04/06)
Activation of [FeCl(dppe)Cp] (1) by chloride abstraction with Na[BArX4] (X = F, [B(3,5-(CF3)2-C6H3)4]; X = Cl, [B(3,5-Cl2-C6H3)4]) permits reactions with a range of nitro aromatics, RC6H4NO2 (R = halogen, Me, OMe, NO2 or NMe2), to give the cationic iron nitroso complexes [Fe{N(O)-C6H4R}(dppe)Cp][BArX4]) ([3][BArX4]). Similar reactions of 1 and Na[BArX4] with [Fe(NCC6H4NO2)(dppe)Cp][BArX4] gave bimetallic [{Fe(dppe)Cp}2{μ-NCC6H4N(O)}][BArF4]2. However, reactions of 1 and Na[BArX4] with 4-nitrophenol gave the first example of the bench-stable iron half-sandwich phenolate complex [Fe(OC6H4NO2)(dppe)Cp]+ rather than NO2 activation. The formation of complexes [3]+ likely proceeds via the unusual blue bimetallic species [{Fe(dppe)Cp}2{μ,κ2O,O′-O2NAr}]2+. This compound undergoes N-O bond cleavage, resulting in [3]+ and a FeIV=O species, which reacts via an internal C-H activation of the dppe ligand to give [FeIII(κ3O,P,P′-P(2-O-C6H4)(Ph)-C2H4-PPh2)Cp]+. Complexes [3]+ are stable under ambient conditions, are readily purified by column chromatography and can be isolated in up to 50% yield, considering that 0.5 equiv of 1 is required as the oxygen acceptor.
