33554-47-1 Usage
Description
7-HYDROXY-5-METHOXY-2-PHENYL-CHROMEN-4-ONE, also known as 7-Hydroxy-5-methoxy-2-phenyl-4H-chromen-4-one (CAS# 33554-47-1), is a flavenoid derived from various plant sources. Flavonoids are a class of compounds known for their broad pharmacological activity, which includes binding to biomolecules such as enzymes, hormone carriers, and DNA, chelating transition metal ions, catalyzing electron transport, and scavenging free radicals. This particular flavenoid is characterized by its unique chemical structure, which contributes to its diverse range of applications.
Uses
Used in Pharmaceutical Applications:
7-HYDROXY-5-METHOXY-2-PHENYL-CHROMEN-4-ONE is used as a bioactive compound for its ability to bind with various biomolecules, such as enzymes and hormone carriers, and chelate transition metal ions. This makes it a promising candidate for the development of new drugs and therapies.
Used in Antioxidant Applications:
In the field of antioxidant research, 7-HYDROXY-5-METHOXY-2-PHENYL-CHROMEN-4-ONE is used as a free radical scavenger. Its ability to neutralize free radicals can help protect cells from oxidative damage, which is a significant factor in the development of various diseases and aging.
Used in Drug Delivery Systems:
7-HYDROXY-5-METHOXY-2-PHENYL-CHROMEN-4-ONE is also used in the development of drug delivery systems. Its unique chemical properties allow it to be incorporated into various formulations, enhancing the delivery, bioavailability, and therapeutic outcomes of other drugs.
Used in Cosmetics Industry:
In the cosmetics industry, 7-HYDROXY-5-METHOXY-2-PHENYL-CHROMEN-4-ONE is used as an active ingredient for its antioxidant and anti-aging properties. It can be incorporated into skincare products to help protect the skin from environmental damage and promote a more youthful appearance.
Used in Nutraceutical Applications:
7-HYDROXY-5-METHOXY-2-PHENYL-CHROMEN-4-ONE is used as a nutraceutical ingredient for its potential health benefits. It can be added to dietary supplements and functional foods to provide consumers with additional antioxidant support and promote overall health.
Check Digit Verification of cas no
The CAS Registry Mumber 33554-47-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,5,5 and 4 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 33554-47:
(7*3)+(6*3)+(5*5)+(4*5)+(3*4)+(2*4)+(1*7)=111
111 % 10 = 1
So 33554-47-1 is a valid CAS Registry Number.
InChI:InChI=1/C16H12O4/c1-19-14-7-11(17)8-15-16(14)12(18)9-13(20-15)10-5-3-2-4-6-10/h2-9,17H,1H3
33554-47-1Relevant articles and documents
Effects of flavonoids on cell proliferation and caspase activation in a human colonic cell line HT29: An SAR study
Daskiewicz, Jean-Baptiste,Depeint, Flore,Viornery, Lionel,Bayet, Christine,Comte-Sarrazin, Geraldine,Comte, Gilles,Gee, Jennifer M.,Johnson, Ian T.,Ndjoko, Karine,Hostettmann, Kurt,Barron, Denis
, p. 2790 - 2804 (2007/10/03)
A library of 42 natural and synthetic flavonoids has been screened for their effect on cell proliferation and apoptosis in a human colonic cell line (HT-29). Examples of different classes of flavonoids have been screened, and the effects of hydroxylation, methoxylation and/or C-alkylation at various positions in the A- and B-rings have been assessed. Flavones and flavonols possess greater antiproliferative activity than chalcones and flavanones. With respect to structural modification of flavonoids, C-isoprenylation was by far the most effective, with substitution at the 8-position and longer chains, such as geranyl giving the best results. Finally, most compounds that significantly reduced cell survival also increased caspase activity, suggesting that at least part of their antiproliferative activity might be attributable to an apoptotic response.
