33630-25-0

Basic information

• Product Name: 2-Phenyl-4-aminopyrimidine
• Synonyms: 2-Phenyl-4-aminopyrimidine;4-Amino-2-Phenylpyrimidine;2-Phenylpyrimidin-4-amine
• CAS NO: 33630-25-0
• Molecular Formula: C₁₀H₉N₃
• Molecular Weight: 171.19856
• Mol File: 33630-25-0.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 2-Phenyl-4-aminopyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Phenyl-4-aminopyrimidine(33630-25-0)
• EPA Substance Registry System: 2-Phenyl-4-aminopyrimidine(33630-25-0)

Safety Data

• Hazardous Substances Data: 33630-25-0(Hazardous Substances Data)

Usage

General Description

2-Phenyl-4-aminopyrimidine, also known as PAP, is a chemical compound with the molecular formula C10H9N3. It is a heterocyclic organic compound that consists of a pyrimidine ring with a phenyl and an amino group attached. PAP has been identified as an intermediate in the synthesis of pharmaceuticals and agrochemicals, and it is used as a building block in the production of various substances. The compound has also shown potential bioactivity and is being studied for its potential applications in medicine and related fields. As a chemical, PAP is important in the field of organic chemistry and is used in various research and industrial processes.

Upstream product

• 14790-42-2 4-chloro-2-phenylpyrimidine 
• 7664-41-7 ammonia 
• 61310-53-0 3-ethoxyacrylonitrile 
• 618-39-3 benzamidin 
• 7461-50-9 2-chloropyrimidin-4-amine 
• 98-80-6 phenylboronic acid 
• 140367-35-7 (E)-[1-cyano-2-(methylsulfanyl)vinyl]triphenylphosphonium iodide 

Downstream Products

• 1246562-29-7 2-(4-acetamidopyrimidin-2-yl)phenyl acetate 
• 33630-29-4 N-(2-phenylpyrimidin-4-yl)acetamide 
• 14790-42-2 4-chloro-2-phenylpyrimidine 
• 1300056-91-0 1-[1-(3-diethylaminopropyl)-1H-indol-3-yl]-3-(2-phenylpyrimidin-4-yl)urea 

Relevant articles and documents

HETEROARYLS AND USES THEREOF

The present invention provides a compound of formula I: and pharmaceutically acceptable salts thereof, wherein X, R1, R2, R3, R4, R5, L1, L2, m, and n, are as described in the specification. Such compounds are inhibitors of VPS34 and thus useful for treating proliferative, inflammatory, or cardiovascular disorders.

The synthesis and evaluation of indolylureas as PKCα inhibitors

PKCα and PKA have crucial but opposing roles in the regulation of calcium handling within myocytes. Identification of compounds that inhibit PKCα, but not PKA, are potential therapeutic targets for the treatment of heart disease. The synthesis of indolylureas are described, and a compound displaying nanomolar inhibition towards PKCα with significant selectivity over PKA has been identified.

11B-HSD1 inhibitors for the treatment of diabetes

Compounds of the formula (I): as well as pharmaceutically acceptable salts and esters thereof, wherein R1 to R5 have the significance given in claim 1 can be used in the form of pharmaceutical compositions.