33671-37-3 Usage
Description
5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-one, also known as Desmethylclotiazepam, is a thienodiazepine compound. It is an active metabolite of clotiazepam, a medication with central nervous depressant and anxiolytic properties. 5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-one is primarily used for research and forensic applications due to its analytical reference standard status. As an off-white solid, it plays a significant role in the study and understanding of the parent drug's effects and metabolism.
Uses
Used in Pharmaceutical Research:
5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-one is used as a research compound for understanding the pharmacological properties, metabolism, and potential therapeutic applications of clotiazepam. Its role as an active metabolite helps researchers investigate the drug's mechanism of action, efficacy, and safety profile.
Used in Forensic Applications:
In the forensic field, 5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-one is utilized as a reference standard for the identification and quantification of clotiazepam and its metabolites in biological samples. This aids in the detection of the drug in cases of drug abuse, overdose, or intoxication, as well as in post-mortem toxicology.
Used in Drug Metabolism Studies:
As an active metabolite of clotiazepam, 5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-one is used in drug metabolism studies to explore the metabolic pathways and enzyme interactions involved in the conversion of the parent drug to its metabolites. This information is crucial for optimizing drug dosages and understanding potential drug-drug interactions.
Used in the Development of New Therapeutics:
The study of 5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-one may also contribute to the development of new therapeutic agents with improved pharmacological properties. By understanding the structure-activity relationships and the metabolic fate of this compound, researchers can design more effective and safer medications for the treatment of anxiety and other related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 33671-37-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,6,7 and 1 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 33671-37:
(7*3)+(6*3)+(5*6)+(4*7)+(3*1)+(2*3)+(1*7)=113
113 % 10 = 3
So 33671-37-3 is a valid CAS Registry Number.
InChI:InChI=1/C15H13ClN2OS/c1-2-9-7-11-14(10-5-3-4-6-12(10)16)18-13(19)8-17-15(11)20-9/h3-7H,2,8H2,1H3,(H,18,19)
