3383-79-7

Basic information

• Product Name: 2-(2-chloroethoxy)naphthalene
• CAS NO: 3383-79-7
• Molecular Formula: C₁₂H₁₁ClO
• Molecular Weight: 206.6681
• Mol File: 3383-79-7.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 332.8°C at 760 mmHg
• Flash Point: 155.6°C
• Density: 1.177g/cm³
• Vapor Pressure: 0.000276mmHg at 25°C
• Refractive Index: 1.602
• CAS DataBase Reference: 2-(2-chloroethoxy)naphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-chloroethoxy)naphthalene(3383-79-7)
• EPA Substance Registry System: 2-(2-chloroethoxy)naphthalene(3383-79-7)

Safety Data

• Hazardous Substances Data: 3383-79-7(Hazardous Substances Data)

Usage

Appearance

Colorless to light yellow

Odor

Strong, aromatic

Chlorinated derivative

Contains a chloroethoxy group attached to one of the naphthalene rings

Uses

Intermediate in the production of various chemicals (pesticides, pharmaceuticals, dyes), solvent, synthesis of other organic compounds

Safety precautions

May cause irritation to skin, eyes, and respiratory system upon contact or inhalation

Upstream product

• 93-20-9 2-(2-naphthalenyloxy)ethanol 
• 80-41-1 2-chloroethyl tosylate 
• 135-19-3 β-naphthol 
• 107-04-0 1-Bromo-2-chloroethane 
• 50890-51-2 2-chloroethyl methyl sulfone 
• 107-07-3 2-chloro-ethanol 

Downstream Products

• 102946-33-8 1-(2-[2]naphthyloxy-ethyl)-4-phenyl-piperidine-4-carboxylic acid ethyl ester 
• 138841-14-2 3-[2-(Naphthalen-2-yloxy)-ethyl]-3H-quinazolin-4-one 
• 63917-98-6 ethyl-(2-chloro-ethyl)-(2-[2]naphthyloxy-ethyl)-amine; hydrochloride 
• 29488-59-3 1-(2-(naphthalen-2-yloxy)ethyl)-4-phenylpiperazine 

Relevant articles and documents

Synthesis and antimicrobial activity of dithiocarbamates of ω-Substituted (2-naphthyloxy)alkanes

A series of dithiocarbamates of ω-substituted (2-naphthyloxy) alkanes was developed through condensation of 2-(2-chloro-alkoxy)-naphthalene to various kinds of aliphatic, aromatic, alicyclic, heterocyclic primary and secondary amines employing benzyl trimethyl ammonium hydroxide in catalytic quantity (Triton-B/CS2 system) afforded desired products in high yields (82-98 %). The complete series of synthesized compounds (4-48) were evaluated for antimicrobial activity through microdilution method using various bacterial and fungal strains. The antifungal and antibacterial values were estimated as MIC values. Fluconazole and ciprofloxacin [16 to 0.03 μg/ mL] were used as the standard antifungal and antibacterial drug, respectively. Out of series of evaluated compounds, some of these compounds such as compounds 28, 29, 30, 31, 32, 33 have displayed maximum potency which is comparable to standard drugs.

METHOD FOR PRODUCING POTASSIUM SALT, AND POTASSIUM SALT

PROBLEM TO BE SOLVED: To provide a method that makes it possible to efficiently produce a halogen compound useful as a precursor of a compound that can be used suitably for optical materials in general. SOLUTION: A method for producing potassium salt includes the step for producing potassium salt represented by formula (1) by the reaction between a compound represented by formula (3), a cyclic carbonate ester compound, and potassium carbonate. [R2 is an aromatic ring-containing group having C constituting an aromatic ring at a binding site to O; n is 1 or 2; R1 independently represents an alkylene group]. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT

MANUFACTURING METHOD OF HALOGEN COMPOUND, MANUFACTURING METHOD OF POTASSIUM SALT AND POTASSIUM SALT

PROBLEM TO BE SOLVED: To provide a method capable of manufacturing a halogen compound useful as a precursor of a compound capable of being preferably used especially for optical system materials generally with high efficiency. SOLUTION: There is provided a manufacturing method of a halogen compound including a process of reacting a compound represented by the following formula (1) and a halogenation agent to produce a halogen compound represented by the following formula (2). In the formula (1), R1 is a linear or branched alkylene group, R2 is an aromatic ring-containing group having a carbon atom constituting an aromatic ring at a binding part with an oxygen atom represented in the formula, n is 1 or 2 and two of R1s may same or different when n is 2. In the formula (2), X is a halogen atom. COPYRIGHT: (C)2016,JPOandINPIT