338389-18-7Relevant articles and documents
Cyclohexenonic long-chain fatty alcohols as neuronal growth stimulators
Luu, Bang,Gonzalez De Aguilar, Jose-Luis,Girlanda-Junges, Celine
, p. 1439 - 1460 (2007/10/03)
Neurotrophic factors play an important role in the development and maintenance of neurons, thus providing a suitable therapeutic approach for the treatment of neurodegenerative diseases. However, their clinical use has revealed problematic because of a number of technical and biological disadvantages. Among the different strategies proposed to overcome such difficulties, the search for non-peptide substances with neurotrophic potential is giving promising results. Here we will expose major findings in this field, drawing special attention to cyclohexenonic long-chain fatty alcohols, a novel family of compounds that promote neuronal survival and neurite outgrowth.