340023-12-3

Basic information

• Product Name: 4-hydroxymethylbicyclo[2.2.2]octane-1-carboxylic acid benzyl ester
• Synonyms: 4-hydroxymethylbicyclo[2.2.2]octane-1-carboxylic acid benzyl ester
• CAS NO: 340023-12-3
• Molecular Weight: 274.36
• Mol File: 340023-12-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-hydroxymethylbicyclo[2.2.2]octane-1-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-hydroxymethylbicyclo[2.2.2]octane-1-carboxylic acid benzyl ester(340023-12-3)
• EPA Substance Registry System: 4-hydroxymethylbicyclo[2.2.2]octane-1-carboxylic acid benzyl ester(340023-12-3)

Safety Data

• Hazardous Substances Data: 340023-12-3(Hazardous Substances Data)

Upstream product

• 828-52-4 4-(hydroxymethyl)bicyclo[2.2.2]octane-1-carboxylic acid 
• 100-39-0 benzyl bromide 

Downstream Products

• 340023-13-4 4-formylbicyclo[2.2.2]octane-1-carboxylic acid benzyl ester 

Relevant articles and documents

Adenosine receptor antagonists and methods of making and using the same

The invention is based on the discovery that compounds of Formula I are unexpectedly highly potent and selective inhibitors of the adenosine A1receptor. Adenosine A1antagonists can be usefull in the prevention and/or treatment of numerous diseases, including cardiac and circulatory disorders, degenerative disorders of the central nervous system, respiratory disorders, and many diseases for which diuretic treatment is suitable. In one embodiment, the invention features a compound of formula I: wherein: R3is an optionally substituted bicyclic, tricylic, or pentacyclic group selected from: ?and wherein R1, R2, R6, X1, X2, and Z are as described in the specification.