34102-86-8

Basic information

• Product Name: Pyridazine, 3,6-bis(4-chlorophenyl)-
• CAS NO: 34102-86-8
• Molecular Formula: C16H10Cl2N2
• Molecular Weight: 301.175
• Mol File: 34102-86-8.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Pyridazine, 3,6-bis(4-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridazine, 3,6-bis(4-chlorophenyl)-(34102-86-8)
• EPA Substance Registry System: Pyridazine, 3,6-bis(4-chlorophenyl)-(34102-86-8)

Safety Data

• Hazardous Substances Data: 34102-86-8(Hazardous Substances Data)

Upstream product

• 1289596-45-7 1,4-bis(4-chlorophenyl)-2-hydroxybutane-1,4-dione 
• 4996-21-8 1-(4-chloro-phenyl)-2,2-dihydroxy-ethanone 
• 99-91-2 para-chloroacetophenone 
• 1679-18-1 4-Chlorophenylboronic acid 
• 20698-04-8 3,6-diiodopyridazine 
• 141-30-0 3,6-dichlorpyridazine 
• 23080-23-1 1,5-bis(4-chlorophenyl)-3-thiapentane-1,5-dione 
• 128256-29-1 C₁₄H₁₂BrClN₂O₂S 
• 89523-62-6 (4-chlorophenyl)zinc(II) chloride 
• 536-38-9 4-chlorobenzoylmethyl bromide 
• 64-17-5 ethanol 
• 27297-60-5 (Z)-1,4-bis(4-chlorophenyl)but-2-ene-1,4-dione 
• 7803-57-8 hydrazine hydrate 
• 64-19-7 acetic acid 

Relevant articles and documents

Novel tandem reactions of 2,2′-sulfonylbis(1,3-diarylprop-2-en-1-ones) with hydrazine: Formation of 3,6-diarylpyridazines and 3,5-diarylpyrazoles

The 2,2′-sulfonylbis(1,3-diarylprop-2-en-1-ones) undergo tandem reactions with hydrazine affording 3,6-diarylpyridazines and 3,5-diarylpyrazoles unexpectedly, the latter predominating.

Efficient Suzuki-Miyaura mono-arylation of symmetrical diiodo(hetero)arenes

A reliable protocol for converting 1,4-diiodo-2,3,5,6-tetrafluorobenzene into 1-(hetero)aryl-4-iodo-2,3,5,6-tetrafluorobenzene derivatives has been lacking in the literature. We have identified optimal conditions to achieve this conversion in good yields and have minimized formation of the bis-coupling product. The newly identified protocol involving the use of a syringe pump has been extended to other symmetrical diiodo(hetero)arenes.

Highly selective mono-substitution in Pd-catalyzed cross-coupling reactions of 3,6-dichloropyridazine with organozinc compounds

Pd-catalyzed cross-coupling reactions of 3,6-dichloropyridazine (1) with benzyl, aryl, and alkyl organozinc compounds led to selective mono-substitution of one of the chlorine atoms. The subsequent cross-coupling of the resulting monochlorides with RZnCl afforded unsymmetrical 3,6-carbon-disubstituted pyridazines.