34244-81-0

Basic information

• Product Name: 2,6,7-Trimethyl-4(3H)-pteridinone
• Synonyms: 2,6,7-Trimethyl-4(3H)-pteridinone
• CAS NO: 34244-81-0
• Molecular Formula: C₉H₁₀N₄O
• Molecular Weight: 0
• Mol File: 34244-81-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,6,7-Trimethyl-4(3H)-pteridinone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6,7-Trimethyl-4(3H)-pteridinone(34244-81-0)
• EPA Substance Registry System: 2,6,7-Trimethyl-4(3H)-pteridinone(34244-81-0)

Safety Data

• Hazardous Substances Data: 34244-81-0(Hazardous Substances Data)

Upstream product

• 39906-04-2 5-amino-4,6-dichloro-2-methylpyrimidine 
• 933-80-2 6-chloro-2-methylpyrimidine -4,5-diamine 
• 431-03-8 dimethylglyoxal 
• 5442-02-4 5,6-diamino-2-methylpyrimidin-4(3H)-one sulfate 
• 45741-61-5 5,6-diamino-2-methylpyrimidin-4(3H)-one 

Downstream Products

• 1268609-41-1 [2-(4-methoxyphenyl)-ethyl]-(2,6,7-trimethylpteridin-4-yl)-amine 

Relevant articles and documents

Reduced 2-Methyl-4-oxo, 2-Methylamino-4-oxo, 2-Methylthio-4-oxo and 2-Amino-4-thioxo 6,7-Dimethylpteridines, and 6,8-Dimethylpterin as Substrates for Dihydropteridine Reductase

The syntheses of unsubstituted (4), 6-methyl- (6), cis-6,7-dimethyl- (8), cis-2,6,7-trimethyl- (10), cis-6,7-dimethyl-2-thioxo-(1H)- (12) and cis-6,7-dimethyl-2-methylthio- (13) 5,6,7,8-tetrahydropteridin-4(3H)-one and the deuterated derivatives (5), (7), (9) and (14), and a cis and trans mixture of 2-amino-6,7-dimethyl-5,6,7,8-tetrahydropteridin-4(3H)-thione (11) are described.The existence of transient quinonoid species (15)-(17) had been previously demonstrated by showing that they are substrates for the enzyme dihydropteridine reductase from human brain.We report that the transient quinonoid species cis-2,6,7-trimethyl- (18), cis-2-methylthio-6,7-dimethyl- (25), cis-2-methylamino-6,7-dimethyl- (26), and 2-amino-6,8-dimethyl- (29) 7,8-dihydropteridin-4(6H)-one, and 2-amino-6,7-dimethyl-7,8-dihydropteridin-4(6H)-thione (28), but not cis-6,7-dimethyl-2-thio-7,8-dihydropteridin-4(6H)-one (27) are substrates for this enzyme showing that a variety of substituents in position 2 of the pteridine ring can be tolerated, and confirming that the predominant tautomer (1) of the quinonoid species in aqueous solution is also the reactive tautomer at the active site of this enzyme.

PTERIDINES AND THEIR USE AS AGROCHEMICALS

The present disclosure relates to 1- or 2-(4-(aryloxy)-phenyl)ethylamino-, oxy- or sulfanyl)pteridines and 1- or 2-(4-(heteroaryloxy)-phenyl)ethylamino-, oxy- or sulfanyl)pteridines and their use as agrochemicals and animal health products.