343312-39-0

Basic information

• Product Name: cyclo(-D(tBu)-f-K(Aloc)-R(Pmc)-G-)
• Synonyms: cyclo(-D(tBu)-f-K(Aloc)-R(Pmc)-G-)
• CAS NO: 343312-39-0
• Molecular Weight: 1010.22
• Mol File: 343312-39-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: cyclo(-D(tBu)-f-K(Aloc)-R(Pmc)-G-)(CAS DataBase Reference)
• NIST Chemistry Reference: cyclo(-D(tBu)-f-K(Aloc)-R(Pmc)-G-)(343312-39-0)
• EPA Substance Registry System: cyclo(-D(tBu)-f-K(Aloc)-R(Pmc)-G-)(343312-39-0)

Safety Data

• Hazardous Substances Data: 343312-39-0(Hazardous Substances Data)

Upstream product

• 71989-14-5 Fmoc-(tBu)Asp-OH 
• 86123-10-6 Fmoc-D-Phe-OH 
• 146982-27-6 (S)-6-allyloxycarbonylamino-2-(9H-fluoren-9-ylmethoxycarbonylamino)-hexanoic acid 

Downstream Products

• 696660-84-1 [(2S,5R,8S,11S)-8-[4-((S)-2-Amino-3-hydroxy-propionylamino)-butyl]-5-benzyl-11-(3-guanidino-propyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]-acetic acid 
• 343312-27-6 cyclo(-Gly-Asp-D-Phe-Lys(CO-CH₂ONH₂)-Arg-) 
• 343312-28-7 cyclo(-Gly-Asp-D-Phe-Lys(CO-COH)-Arg-) 
• 161552-03-0 [(2S,5R,8S,11S)-8-(4-Amino-butyl)-5-benzyl-11-(3-guanidino-propyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]-acetic acid 
• 388633-54-3 C₄₅H₆₇N₉O₁₀S 

Relevant articles and documents

A convenient access to αVβ3/αVβ5 integrin ligand conjugates: Regioselective solid-phase functionalisation of an RGD based peptide

The cyclopeptide (-RGDfK-) is a potent and selective αVβ3/αVβ5 integrin ligand. A methodology for the conjugation of cyclo(-RGDfK-) through the regioselective derivatisation of lysine side chains, either in solution or directly on the solid support, is described. This provides a rapid and flexible chemical entry to conjugated integrin ligands bearing reporter groups for biological investigations or reactive chemical functions for the preparation of new vector systems.