343852-60-8

Basic information

• Product Name: 2-phenylcyclopentan-1-ol
• Synonyms: 2-phenylcyclopentan-1-ol
• CAS NO: 343852-60-8
• Molecular Weight: 162.232
• Mol File: 343852-60-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-phenylcyclopentan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenylcyclopentan-1-ol(343852-60-8)
• EPA Substance Registry System: 2-phenylcyclopentan-1-ol(343852-60-8)

Safety Data

• Hazardous Substances Data: 343852-60-8(Hazardous Substances Data)

Upstream product

• 42086-64-6 trans-2-phenylcyclopentan-1-ol 
• 286-20-4 cyclohexane-1,2-epoxide 
• 285-67-6 Cyclopentene oxide 
• 100-58-3 phenylmagnesium bromide 
• 100-59-4 phenylmagnesium chloride 
• 60895-01-4 3(S)-acetoxy-5-(R)-hydroxy-cyclopent-1-ene 
• 414869-14-0 (1S,2S)-2-Phenyl-cyclopent-3-enol 
• 825-54-7 cyclopent-1-en-1-ylbenzene 

Downstream Products

• 1198-34-1 2-Phenylcyclopentanone 
• 344463-12-3 (1S,2S)-cis-propane-2-sulfonic acid [2-(4-iodo-phenyl)-cyclopentyl]-amide 
• 344463-13-4 (1R,2R)-cis-propane-2-sulfonic acid [2-(4-iodo-phenyl)-cyclopentyl]-amide 

Relevant articles and documents

p-Toluenesulfonic acid catalysed fluorination of α-branched ketones for the construction of fluorinated quaternary carbon centres

A p-toluenesulfonic acid catalyzed fluorination of α-branched ketones for the construction of fluorinated quaternary carbon centers has been developed, featuring a broad substrate scope, environmentally benign reaction conditions, and operational simplicity.

Discovery of N-(2-aryl-cyclohexyl) substituted spiropiperidines as a novel class of GlyT1 inhibitors

Screening of the Roche compound library led to the identification of cis-N-(2-phenyl-cyclohexyl)-spiropiperidine 1 as structurally novel GlyT1 inhibitor. The SAR, which was developed in this series, resulted in the discovery of highly potent compounds displaying excellent selectivity against the GlyT2 isoform.

Evidence for the formation of a new five-membered ring cyclic allene: Generation of 1-cyclopenta-1,2-dien-1-ylbenzene

Treatment of 1-(2-iodocyclopent-1-en-1-yl) benzene (13), dissolved in benzene, with potassium t-butoxide resulted in the formation of 1-(2-phenylcyclopent-1-en-1-yl) benzene (15) and 1-cyclopent-1-en-1-yl benzene (5) in a ratio of 1:1.