34397-00-7

Basic information

• Product Name: Nsc79667
• Synonyms: Nsc79667;7N-[1-(2-Carboxy)ethyl]allopurinol;1,6-Dihydro-6-oxo-9H-purine-9-propanoic Acid;9H-Hypoxanthin-9-ylpropionic Acid;3-(6-oxo-3H-purin-9-yl)propanoic acid
• CAS NO: 34397-00-7
• Molecular Formula: C8H8N4O3
• Molecular Weight: 208.17412
• Product Categories: Bases & Related Reagents;Nucleotides;Nucleotides, Bases & Related Reagents
• Mol File: 34397-00-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 275-277?C (dec.)
• Boiling Point: 599.8°C at 760 mmHg
• Flash Point: 316.5°C
• Appearance: /
• Density: 1.71g/cm³
• Vapor Pressure: 3.1E-15mmHg at 25°C
• Refractive Index: 1.762
• Storage Temp.: Refrigerator
• Solubility: Aqueous Acid (Slightly)
• CAS DataBase Reference: Nsc79667(CAS DataBase Reference)
• NIST Chemistry Reference: Nsc79667(34397-00-7)
• EPA Substance Registry System: Nsc79667(34397-00-7)

Safety Data

• Hazardous Substances Data: 34397-00-7(Hazardous Substances Data)

Usage

Description

Nsc79667, also known as 7N-[1-(2-Carboxy)ethyl]allopurinol, is a compound with the CAS number 34397-00-7. It is characterized by its pale beige solid appearance and is primarily used in organic synthesis.

Uses

Used in Organic Synthesis:
Nsc79667 is used as a synthetic compound for various chemical reactions and processes in the field of organic synthesis. Its unique structure allows it to be a valuable building block or intermediate in the creation of more complex molecules and compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Nsc79667 is used as a precursor or intermediate in the development of new drugs. Its chemical properties make it a promising candidate for the synthesis of therapeutic agents, potentially leading to the discovery of novel medications with improved efficacy and safety profiles.
Used in Research and Development:
Nsc79667 is also utilized in research and development settings, where it can be employed to study the properties and behavior of various chemical reactions. This can contribute to a better understanding of the underlying mechanisms and help in the design of more efficient and targeted synthetic pathways.

InChI:InChI=1/C8H8N4O3/c13-5(14)1-2-12-4-11-6-7(12)9-3-10-8(6)15/h3-4H,1-2H2,(H,13,14)(H,9,10,15)

Upstream product

• 7083-40-1 3-(6-aminopurine-9-yl)-propionic acid ethyl ester 
• 66224-66-6 adenine 
• 95789-89-2 ethyl 3-(1,6-dihydro-6-oxo-9H-purin-9-yl)propanoate 

Downstream Products

• 138117-79-0 4-[[3-(1,6-dihydro-6-oxo-9H-purin-9-yl)-1-oxopropyl]amino]benzoic acid,ethyl ester 

Relevant articles and documents

A new method for synthesis and angiogenic evaluation of leteprinim potassium and its novel analogs

We developed a novel pathway for the successful synthesis of leteprinim potassium 1, which is one of the candidate substances for treating Alzheimer's disease, and subsequently synthesized 4 types of corresponding novel derivatives 2-5 that have hypoxanthine or 2-chloro-6-aminopurine as the nucleobase. We then determined the angiogenic activity of these compounds by using human umbilical vein endothelial cells. Compounds 1-4 showed no angiogenic potencies judging from statistical analysis, student's t-test.

9-substituted hypoxanthine bi-functional compounds and their neuroimmunological methods of use

Novel bi-functional pharmaceutical compounds, particularly novel 9-substituted hypoxanthines of the general formula: STR1 where R is a neurologically active moiety, are described as pharmaceutical agents for treating neuroimmunologic disorders in mammals. Novel methods for the utilization of these compounds are also disclosed. These compounds exhibit uniquely dose-dependent, synergistic biological properties and are particularly useful for treating interrelated physiological systems.