346577-99-9

Basic information

• Product Name: (2S,4S)-2-(biphenyl-4-yl)-4-methyl-5-oxo-oxazolidine-3-carboxylic acid isobutyl ester
• Synonyms: (2S,4S)-2-(biphenyl-4-yl)-4-methyl-5-oxo-oxazolidine-3-carboxylic acid isobutyl ester
• CAS NO: 346577-99-9
• Molecular Weight: 353.418
• Mol File: 346577-99-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,4S)-2-(biphenyl-4-yl)-4-methyl-5-oxo-oxazolidine-3-carboxylic acid isobutyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S)-2-(biphenyl-4-yl)-4-methyl-5-oxo-oxazolidine-3-carboxylic acid isobutyl ester(346577-99-9)
• EPA Substance Registry System: (2S,4S)-2-(biphenyl-4-yl)-4-methyl-5-oxo-oxazolidine-3-carboxylic acid isobutyl ester(346577-99-9)

Safety Data

• Hazardous Substances Data: 346577-99-9(Hazardous Substances Data)

Upstream product

• 3218-36-8 4-Phenylbenzaldehyde 
• 543-27-1 isobutyl chloroformate 
• 183140-29-6 N-isobutyloxycarbonyl-(S)-alanine 

Downstream Products

• 346578-00-5 (2S,4R)-4-Benzyl-2-biphenyl-4-yl-4-methyl-5-oxo-oxazolidine-3-carboxylic acid isobutyl ester 
• 346578-01-6 (2S,4R)-2-Biphenyl-4-yl-4-(4-bromo-benzyl)-4-methyl-5-oxo-oxazolidine-3-carboxylic acid isobutyl ester 
• 346578-03-8 (R)-3-(4-bromophenyl)-2-isobutoxycarbonylamino-2-methylpropionic acid methyl ester 
• 346578-02-7 (R)-2-isobutoxycarbonylamino-2-methyl-3-phenylpropionic acid methyl ester 

Relevant articles and documents

Crystallization-induced asymmetric transformations and self-regeneration of stereocenters (SROSC): Enantiospecific synthesis of α-benzylalanine and hydantoin BIRT-377

N-Isobutoxycarbonyl protected L-alanine was condensed with 4-phenylbenzaldehyde in a crystallization-controlled process to give the corresponding cis-oxazolidinone derivative as the sole product in high yield; this underwent enolization and benzylation wi