349-65-5 Usage
Description
2-Methoxy-5-(trifluoromethyl)aniline is an organic compound characterized by its beige-greyish to brownish crystalline powder appearance. It is a derivative of aniline, featuring a methoxy group at the 2nd position and a trifluoromethyl group at the 5th position on the aromatic ring. 2-Methoxy-5-(trifluoromethyl)aniline is known for its unique chemical properties, which make it a versatile building block in various chemical synthesis processes.
Uses
Used in Chemical Synthesis:
2-Methoxy-5-(trifluoromethyl)aniline is used as a synthetic intermediate for the production of various pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique substitution pattern and reactivity make it a valuable component in the synthesis of complex organic molecules, particularly those with potential applications in the life sciences and materials industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Methoxy-5-(trifluoromethyl)aniline is used as a key building block for the development of novel drug candidates. Its presence in the molecular structure can influence the pharmacokinetic and pharmacodynamic properties of the resulting compounds, potentially leading to improved efficacy and selectivity in targeting specific biological pathways.
Used in Agrochemical Industry:
2-Methoxy-5-(trifluoromethyl)aniline is also utilized in the agrochemical industry for the synthesis of new pesticides and other crop protection agents. Its incorporation into these molecules can enhance their performance, providing more effective pest control and crop protection with reduced environmental impact.
Used in Materials Science:
In the field of materials science, 2-Methoxy-5-(trifluoromethyl)aniline can be employed in the development of advanced materials with specific properties, such as improved thermal stability, chemical resistance, or electronic properties. Its unique chemical structure allows for the creation of novel polymers, coatings, and other materials with tailored characteristics for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 349-65-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,4 and 9 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 349-65:
(5*3)+(4*4)+(3*9)+(2*6)+(1*5)=75
75 % 10 = 5
So 349-65-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H8F3NO/c1-13-7-3-2-5(4-6(7)12)8(9,10)11/h2-4H,12H2,1H3
349-65-5Relevant articles and documents
Method for preparing 4-bromo-2-methoxy-5-trifluoromethyl benzaldehyde
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, (2022/04/03)
The invention provides a method for preparing 4-bromo-2-methoxy-5-(trifluoromethyl) benzaldehyde, and belongs to the field of synthesis processes. The method comprises the following steps: carrying out formylation reaction on a compound VI, so as to obtain the 4-bromo-2-methoxy-5-trifluoromethyl benzaldehyde. The method for preparing the 4-bromine-2-methoxy-5-trifluoromethyl benzaldehyde has the advantages of easily available raw materials, mild reaction conditions, simple steps, low cost, safety, no toxicity and easiness in large-scale production, can obviously improve the total yield and purity of the target product 4-bromine-2-methoxy-5-trifluoromethyl benzaldehyde, and has wide application prospects.
ONE POT PROCESS FOR THE CONVERSION OF AROYL CHLORIDES TO ACYL THIOUREAS
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Page/Page column 10; 15, (2014/06/24)
The present invention disclose an improved one pot process for synthesis of acyl thioureas of formula (I), with yield greater than 80%, from aroyl chlorides of formula (I) wherein, R' is an aryl or a heteroarylene group substituted with one or more groups selected from hydrogen, alkyl, alkylene, alkynyl, alkoxy, alkenyloxy, halo, hydroxyl, nitro, amino, carboxyl, ester, halogenated hydrocarbon or an aryl or heteroaryl; R" and R"' are selected independently from hydrogen, alkyl, alkylene, alkynyl, alkoxy, alkenyloxy, halo, hydroxyl, nitro, amino or halogenated hydrocarbon.
Palladium-catalyzed silane/siloxane reductions in the one-pot conversion of nitro compounds into their amines, hydroxylamines, amides, sulfonamides, and carbamates
Rahaim Jr., Ronald J.,Maleczka Jr., Robert E.
, p. 3316 - 3340 (2008/09/17)
A combination of palladium(II) acetate, aqueous potassium fluoride, and polymethylhydrosiloxane (PMHS) facilitates the room-temperature reduction of aromatic nitro compounds to anilines. These reactions tend to be quick (30 min), high-yielding, and tolerate a range of other functional groups. Replacement of PMHS/KF with triethylsilane allows for the reduction of aliphatic nitro compounds to their corresponding hydroxylamines. Depending on the substrate, both conditions can allow for the in situ conversion of the product amines into amides, sulfonamides, and carbamates. Georg Thieme Verlag Stuttgart.
