35378-76-8

Basic information

• Product Name: 2,5-Octadiyn-1-ol
• Synonyms: 2,5-Octadiyn-1-ol
• CAS NO: 35378-76-8
• Molecular Formula: C₈H₁₀O
• Molecular Weight: 122.1644
• Product Categories: Glycerols, Fatty Acid Derivatives & Lipids, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 35378-76-8.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 237.789 °C at 760 mmHg
• Flash Point: 107.685 °C
• Appearance: /
• Density: 0.98 g/cm³
• Storage Temp.: Amber Vial, -86°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
• CAS DataBase Reference: 2,5-Octadiyn-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Octadiyn-1-ol(35378-76-8)
• EPA Substance Registry System: 2,5-Octadiyn-1-ol(35378-76-8)

Safety Data

• Hazardous Substances Data: 35378-76-8(Hazardous Substances Data)

Usage

Description

2,5-Octadiyn-1-ol is an organic compound characterized by a unique structure that features a triple bond between the second and fifth carbon atoms, along with a hydroxyl group attached to the first carbon atom. This distinctive molecular arrangement endows 2,5-Octadiyn-1-ol with specific chemical properties that make it a versatile reagent in various synthesis processes.

Uses

Used in Chemical Synthesis:
2,5-Octadiyn-1-ol is used as a reagent for the preparation of a wide range of biological and organometallic compounds. Its triple bond and hydroxyl group provide a foundation for various chemical reactions, enabling the synthesis of complex molecules with potential applications in different fields.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,5-Octadiyn-1-ol is utilized as a key intermediate in the synthesis of drug molecules. Its unique structure allows for the creation of novel compounds with specific therapeutic properties, contributing to the development of new medications for various diseases.
Used in Organic Chemistry Research:
2,5-Octadiyn-1-ol serves as a valuable research tool in organic chemistry, where it is employed to study the reactivity and behavior of molecules containing triple bonds and hydroxyl groups. This research can lead to a better understanding of chemical reactions and the development of new synthetic methods.
Used in Material Science:
In the field of material science, 2,5-Octadiyn-1-ol can be used to develop new types of materials with unique properties. Its ability to participate in various chemical reactions allows for the creation of materials with tailored characteristics, such as improved strength, flexibility, or chemical resistance.
Overall, 2,5-Octadiyn-1-ol is a versatile reagent with applications in multiple industries, including pharmaceuticals, chemical synthesis, organic chemistry research, and material science. Its unique structure and chemical properties make it an essential component in the development of new compounds and materials with diverse applications.

Upstream product

• 13280-07-4 4-chlorobut-2-yn-1-ol 
• 107-00-6 but-1-yne 
• 16400-32-1 1-bromo-pent-2-yne 
• 107-19-7 propargyl alcohol 
• 34498-11-8 1-iodo-2-pentyne 
• 117606-23-2 2,5-octadiyn-1-ol tetrahydropyranyl ether 
• 6261-22-9 pent-2-yn-1-ol 
• 92666-05-2 toluene-4-sulfonic acid pent-2-ynyl ester 

Downstream Products

• 56797-44-5 (8Z,11Z,14Z)-8,11,14-heptadecatrienal 
• 125112-06-3 4-Bromo-benzoic acid (S)-11-hydroxy-1-((2R,3S)-3-pent-2-ynyl-oxiranyl)-undec-2-ynyl ester 
• 130893-27-5 4-Bromo-benzoic acid (S)-11-oxo-1-((2R,3S)-3-pent-2-ynyl-oxiranyl)-undec-2-ynyl ester 
• 125112-08-5 4-Bromo-benzoic acid (Z)-(S)-10-carboxy-1-[(2R,3S)-((Z)-3-pent-2-enyl)-oxiranyl]-dec-2-enyl ester 
• 125112-07-4 4-Bromo-benzoic acid (S)-10-carboxy-1-((2R,3S)-3-pent-2-ynyl-oxiranyl)-dec-2-ynyl ester 
• 130893-26-4 4-Bromo-benzoic acid (S)-1-((2R,3S)-3-pent-2-ynyl-oxiranyl)-11-(tetrahydro-pyran-2-yloxy)-undec-2-ynyl ester 
• 24880-40-8 eicosatetraenoic acid 
• 2091-28-3 stearidonic acid 
• 132712-70-0 8Z,11Z,14Z,17Z-eicosatetraenoic acid methyl ester 
• 73097-00-4 6,9,12,15-cis-octadecanetetraenoic acid methyl ester 
• 90780-55-5 (±)-(4Z,8E,10Z,13Z,16Z,19Z)-7-hydroxydocosa-4,8,10,13,16,19-hexaenoic acid 
• 5871-06-7 1-bromotetradeca-2,5,8,11-tetrayne 
• 5871-10-3 2,5,8,11-tetradecatetrayne-1-ol 
• 34498-25-4 1-bromo-2,5,8-undecatriyne 

Relevant articles and documents

Total synthesis of (3Z,9Z,6S,7R) and (3Z,9Z,6R,7S)-6,7-epoxy-3,9-octadecadienes

(3Z,9Z,6S,7R)-6,7-epoxy-3,9-octadecadiene (1) and (3Z,9Z,6R,7S)-6,7-epoxy-3,9-octadecadiene (2) have been stereoselectively synthesized in eight steps from 2-pentyn-1-ol with an overall yield of 8%. The key steps involved the Sharpless asymmetric dihydrox

Pheromone Bouquet of the Dried Bean Beetle, Acanthoscelides obtectus (Col.: Chrysomelidae), Now Complete

Male-specific volatile components, released by the dried bean beetle, Acanthoscelides obtectus, were identified as methyl (E,R)-2,4,5-tetradecatrienoate, methyl (2E,4Z,7Z)-2,4,7-decatrienoate, methyl (2E,4Z)-2,4-decadienoate, octadecanal and the sesquiterpenes (3Z,6E)- and (3E,6E)-α-farnesene. In olfactometer bioassays, pure methyl (E,R)-2,4,5-tetradecatrienoate was only weakly attractive to unmated females. However, a blend of the six identified compounds released in physiologically relevant ratios and doses proved to be as active as headspace odours collected from live males.

A Modular, Enantioselective Synthesis of Resolvins D3, E1, and Hybrids

Resolvins D3 and E1 are important signaling molecules in the resolution of inflammation. Here, we report a convergent and flexible strategy to prepare these natural products using Hiyama-Denmark coupling of five- and six-membered cyclic alkenylsiloxanes to connect three resolvin fragments, and control the stereochemistry of the natural product (Z)-alkenes. The modular nature of this approach enables the synthesis of novel resolvin hybrids, opening up opportunities for more-extensive investigations of resolvin biology.

A tea canker-worm pheromone (Z, Z, Z) - 3, 6, 9 - triene synthetic method of eighteen carbon (by machine translation)

The invention relates to a natural [...] pheromone component novel synthesis method, in particular relates to a tea canker-worm pheromone (Z, Z, Z) - 3, 6, 9 - eighteen carbon triene synthetic method, it has [...], is non-toxic and harmless, which belongs to the field of drug synthesis. The invention uses inexpensive and easily obtained a halopropynyl alcohol as the reaction of the starting material, in order to iodo reagent catalytic coupling reaction as a key step, after six-step reaction, smooth synthetic tea canker-worm pheromone (Z, Z, Z) - 3, 6, 9 - eighteen carbon triene, the operation is simple, low cost, easily obtained and cheap materials, mild reaction conditions, high yield, the large scale preparation. (by machine translation)