35794-11-7 Usage
Description
3,5-Dimethylpiperidine is an organic compound with the molecular formula C7H13N. It is a heterocyclic amine with two methyl groups attached to the 3rd and 5th positions of the piperidine ring. 3,5-Dimethylpiperidine is known for its unique chemical properties and versatile applications in various industries.
Uses
Used in Pharmaceutical Industry:
3,5-Dimethylpiperidine is used as a reactant for the synthesis of various pharmaceutical compounds, including substituted bisphenol A derivatives, which act as β-amyloid peptide aggregation inhibitors. These inhibitors are crucial for the development of drugs targeting neurodegenerative diseases such as Alzheimer's.
Used in Biochemical Research:
In the field of biochemical research, 3,5-Dimethylpiperidine serves as a reactant for the synthesis of MMP-13 selective isonipecotamide α-sulfone hydroxamates. These hydroxamates are essential for studying the role of matrix metalloproteinases in various biological processes and diseases.
Used in Organic Synthesis:
3,5-Dimethylpiperidine is used as a reactant for the synthesis of gem-diamines, which are active organocatalysts for biodiesel production. These organocatalysts play a significant role in the development of sustainable and environmentally friendly fuel alternatives.
Used in Immunology:
In the field of immunology, 3,5-Dimethylpiperidine is used as a reactant for the synthesis of benzimidazole inhibitors of the antigen receptor-mediated NF-κB pathway. These inhibitors are vital for understanding the regulation of immune responses and the development of immunomodulatory drugs.
Used in Coordination Chemistry:
3,5-Dimethylpiperidine also serves as a reactant for Mannich reactions to form Ru(II) complexes. These complexes are of interest in coordination chemistry and have potential applications in catalysis and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 35794-11-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,7,9 and 4 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 35794-11:
(7*3)+(6*5)+(5*7)+(4*9)+(3*4)+(2*1)+(1*1)=137
137 % 10 = 7
So 35794-11-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H15N/c1-6-3-7(2)5-8-4-6/h6-8H,3-5H2,1-2H3/p+1/t6-,7-/m0/s1
35794-11-7Relevant articles and documents
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Windle et al.
, p. 2630,2631 (1969)
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Method for synthesizing dimethylpiperidine
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Paragraph 0006-0007, (2020/01/12)
The invention discloses a method for synthesizing dimethylpiperidine. The method comprises the following steps: adding 3,5-dimethylpyridine into a high-pressure kettle, adding an organic solvent and aquantitative catalyst, carrying out heating to 90-160 DEG C, carrying out pressurizing to 3-10 MPa, and introducing hydrogen for reduction. The method is simple and practical in process, is convenient to operate, is high in yield, is non-toxic and harmless, and is suitable for industrial production.
Cobalt-bridged secondary building units in a titanium metal-organic framework catalyze cascade reduction of N-heteroarenes
Feng, Xuanyu,Song, Yang,Chen, Justin S.,Li, Zhe,Chen, Emily Y.,Kaufmann, Michael,Wang, Cheng,Lin, Wenbin
, p. 2193 - 2198 (2019/02/20)
We report here a novel Ti3-BPDC metal-organic framework (MOF) constructed from biphenyl-4,4′-dicarboxylate (BPDC) linkers and Ti3(OH)2 secondary building units (SBUs) with permanent porosity and large 1D channels. Ti-OH groups from neighboring SBUs point toward each other with an O-O distance of 2 ?, and upon deprotonation, act as the first bidentate SBU-based ligands to support CoII-hydride species for effective cascade reduction of N-heteroarenes (such as pyridines and quinolines) via sequential dearomative hydroboration and hydrogenation, affording piperidine and 1,2,3,4-tetrahydroquinoline derivatives with excellent activity (turnover number ~ 1980) and chemoselectivity.