3583-85-5Relevant articles and documents
An efficient base-catalyzed double addition of H-phosphine oxides to alkynes
Yoshimura, Aya,Saga, Yuta,Sato, Yuki,Ogawa, Akiya,Chen, Tieqiao,Han, Li-Biao
, p. 3382 - 3384 (2016)
An efficient base-catalyzed double addition of H-phosphine oxides to alkynes is developed. In the presence of a catalytic amount of a base, the addition of various H-phosphine oxides to both aromatic and aliphatic alkynes took place efficiently to produce the corresponding bisphosphoryl compounds in excellent yields. This method provides an easy direct way to prepare bisphosphine oxides that are of high importance in organic synthesis.
Regioselective Single and Double Hydrophosphination and Hydrophosphinylation of Unactivated Alkynes
Basiouny, Miriam M. I.,Dollard, Deborah A.,Schmidt, Joseph A. R.
, p. 7143 - 7153 (2019/08/26)
A lanthanum-based N,N-dimethylbenzylamine complex was used as a precatalyst for both hydrophosphination and hydrophosphinylation of alkynes under mild conditions. In the case of hydrophosphination, the catalyst induced monoaddition with high regiospecific
T-BuOK-mediated reductive addition of P(O)-H compounds to terminal alkynes forming β-arylphosphine oxides
Zhang, Ji-Shu,Zhang, Jian-Qiu,Chen, Tieqiao,Han, Li-Biao
supporting information, p. 5462 - 5467 (2017/07/12)
A novel and efficient t-BuOK-mediated reductive addition of P(O)-H compounds to terminal alkynes was developed. A variety of β-arylphosphine oxides including the valuable β-heteroarylphosphine oxides were produced in moderate to high yields under mild reaction conditions. This reaction may proceed via a tandem process involving regio-selective double addition and subsequent transfer hydrogenation.
