36318-56-6

Basic information

• Product Name: N-(2-Methylphenyl)-2-imidazolidinimine
• Synonyms: 2-(2-Methylphenylimino)imidazolidine;N-(2-Methylphenyl)-2-imidazolidinimine;4,5-dihydro-N-(2-methylphenyl)-1H-Imidazol-2-amine
• CAS NO: 36318-56-6
• Molecular Formula: C₁₀H₁₃N₃
• Molecular Weight: 175.2303
• Mol File: 36318-56-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 280.1°Cat760mmHg
• Flash Point: 123.2°C
• Appearance: /
• Density: 1.17g/cm³
• Vapor Pressure: 0.00386mmHg at 25°C
• Refractive Index: 1.618
• CAS DataBase Reference: N-(2-Methylphenyl)-2-imidazolidinimine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-Methylphenyl)-2-imidazolidinimine(36318-56-6)
• EPA Substance Registry System: N-(2-Methylphenyl)-2-imidazolidinimine(36318-56-6)

Safety Data

• Hazardous Substances Data: 36318-56-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H13N3/c1-8-4-2-3-5-9(8)13-10-11-6-7-12-10/h2-5H,6-7H2,1H3,(H2,11,12,13)

Upstream product

• 17425-17-1 N-(2-methylphenyl)-methyl dithiocarbamic acid 
• 107-15-3 ethylenediamine 
• 96-45-7 4,5-dihydro-1H-imidazole-2-thiol 
• 95-53-4 o-toluidine 
• 20112-79-2 2-methylthioimidazoline 
• 614-69-7 2-tolyl isothiocyanate 
• 614-78-8 o-tolylthiourea 
• 116072-43-6 dimethyl N-(2-methylphenyl)dithioimidocarbonate 
• 5391-39-9 1-acetylimidazolidin-2-one 
• 19801-35-5 2-ethyl-1-o-tolyl-isothiourea 

Relevant articles and documents

One-pot synthesis of iminoimidazolines under microwave irradiation in solvent-free conditions

Substituted iminoimidazolines were synthesized from a one-pot reaction of aromatic or hetero-aromatic amines with imidazolidine-2-thione under solvent-free conditions using microwave irradiation with good to excellent yields. Copyright Taylor & Francis Group, LLC.

Three-dimensional common-feature hypotheses for octopamine agonist 2-(arylimino)imidazolidines

Three-dimensional pharmacophore hypotheses were built from a set of 10 octopamine (OA) agonist 2-(Arylimino)imidazolidines (AIIs), 2-(Arylimino)thiazolidines (AITs) and 2-(Arylimino)oxazolidines (AIOs). Among the 10 common-featured models generated by program Catalyst/HipHop, a hypothesis including a ring aromatic (RA), a positive ionizable (PI) and three hydrophobic aliphatic (HpA1) features was considered to be important in evaluating the OA-agonist activity. Active OA agonist 2,6-Et2 AII mapped well onto all the RA, PI and HpAl features of the hypothesis. On the other hand, less active compounds were shown to be difficult to achieve the energetically favorable conformation which is found in the active molecules in order to fit the 3-D common-feature pharmacophore models. Taken together, 2,6-Et2-Ph and foramidine structures are important as OA agonists. The present studies on OA agonists demonstrate that a RA, a PI and three HpAl sites located on the molecule seem to be essential for OA-agonist activity. Copyright

Synthesis of 2-Aryliminoimidazolidines and 2-Arylaminobenzimidazoles from Methyl N-Aryldithiocarbamates

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