36448-60-9 Usage
Description
2-methyl-1-thiophen-2-yl-propan-1-one, also known as 2-methyl-1-(2-thienyl)-1-propanone, is an organic compound characterized by the chemical formula C10H12OS. It presents as a yellow to brown liquid, exhibiting a complex aroma that is fruity, sweet, and floral. This versatile chemical is recognized for its role as a key component in the creation of flavors and fragrances, as well as for its utility in the pharmaceutical and agrochemical industries. Additionally, it serves as a valuable intermediate in organic synthesis and acts as a reagent for preparing a variety of compounds. As a ketone containing a sulfur atom, 2-methyl-1-thiophen-2-yl-propan-1-one is an important building block within the chemical industry.
Uses
Used in Flavor and Fragrance Industry:
2-methyl-1-thiophen-2-yl-propan-1-one is utilized as a key ingredient in the development of flavors and fragrances due to its distinctive fruity, sweet, and floral scent. This application capitalizes on its natural aroma to enhance the sensory experience of various consumer products.
Used in Pharmaceutical Industry:
Within the pharmaceutical sector, 2-methyl-1-thiophen-2-yl-propan-1-one is employed as a crucial component in the manufacturing process of certain medications. Its unique chemical structure allows it to contribute to the development of new drugs and therapies.
Used in Agrochemical Industry:
In the agrochemical field, 2-methyl-1-thiophen-2-yl-propan-1-one is used in the production of various agricultural chemicals. Its incorporation aids in the development of products designed to improve crop protection and yield.
Used as an Intermediate in Organic Synthesis:
2-methyl-1-thiophen-2-yl-propan-1-one is recognized for its role as an intermediate in organic synthesis. This position highlights its importance in the synthesis of a wide range of organic compounds, contributing to the advancement of chemical research and product development.
Used as a Reagent in Compound Preparation:
Furthermore, 2-methyl-1-thiophen-2-yl-propan-1-one functions as a reagent for the preparation of different compounds. Its chemical properties make it suitable for facilitating various chemical reactions, thereby expanding its applications across multiple industries.
Check Digit Verification of cas no
The CAS Registry Mumber 36448-60-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,4,4 and 8 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 36448-60:
(7*3)+(6*6)+(5*4)+(4*4)+(3*8)+(2*6)+(1*0)=129
129 % 10 = 9
So 36448-60-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H10OS/c1-6(2)8(9)7-4-3-5-10-7/h3-6H,1-2H3
36448-60-9Relevant articles and documents
Palladium-Catalyzed Synthesis of α-Methyl Ketones from Allylic Alcohols and Methanol
Biswal, Priyabrata,Samser, Shaikh,Meher, Sushanta Kumar,Chandrasekhar, Vadapalli,Venkatasubbaiah, Krishnan
supporting information, p. 413 - 419 (2021/11/01)
One-pot synthesis of α-methyl ketones starting from 1,3-diaryl propenols or 1-aryl propenols and methanol as a C1 source is demonstrated. This one-pot isomerization-methylation is catalyzed by commercially available Pd(OAc)2 with H2O as the only by-product. Mechanistic studies and deuterium labelling experiments indicate the involvement of isomerization of allyl alcohol followed by methylation through a hydrogen-borrowing pathway in these isomerization-methylation reactions.
External-oxidant-free amino-benzoyloxylation of unactivated alkenes of unsaturated ketoximes with: O -benzoylhydroxylamines
Chen, Jiangfei,Zhu, Yan-Ping,Li, Jin-Heng,Wang, Qiu-An
supporting information, p. 5215 - 5218 (2021/05/31)
A new copper-catalyzed two-component amino-benzoyloxylation of unactivated alkenes of unsaturated ketoximes with O-benzoylhydroxylamines as the benzoyloxy sources is developed. Chemoselectivity of this method toward amino-benzoyloxylation or oxy-benzoyloxylation of alkenyl ketoximes relies on the position of the tethered olefins, and provides an external-oxidant-free alkene difunctionalization route that directly utilizes O-benzoylhydroxylamines as the benzoyloxy radical precursors and internal oxidants for the divergent synthesis of cyclic nitrones and isoxazolines.
Method for preparing aryl ketone based on iron-catalyzed free radical-free radical coupling reaction such as ketonic acid decarboxylation and fatty aldehyde de-carbonylation
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Paragraph 0077-0078, (2020/05/05)
The invention discloses a method for preparing an aryl ketone derivative based on a free radical-free radical cross-coupling reaction such as ketonic acid decarboxylation and fatty aldehyde de-carbonylation. The method comprises the following steps: reacting aryl-substituted ketonic acid with fatty aldehyde under the catalytic action of ferric triacetylacetonate to generate an aryl ketone derivative; the gram-grade reaction can be realized by the method only by using 3mol% of an iron catalyst; and the method has the advantages of no need of consumption of a large amount of a Lewis acid catalyst or a stoichiometric organic metal reagent, mild reaction conditions, one-step reaction, few by-products, wide substrate application range and scalable reaction, and overcomes the defects of large catalyst consumption, insufficient functional group tolerance, many by-products and the like in the prior art.
