365462-70-0

Basic information

• Product Name: ethyl 3-amino-4-[(3-cyanophenylamino)methyl]benzoate
• Synonyms: ethyl 3-amino-4-[(3-cyanophenylamino)methyl]benzoate
• CAS NO: 365462-70-0
• Molecular Weight: 295.341
• Mol File: 365462-70-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 3-amino-4-[(3-cyanophenylamino)methyl]benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-amino-4-[(3-cyanophenylamino)methyl]benzoate(365462-70-0)
• EPA Substance Registry System: ethyl 3-amino-4-[(3-cyanophenylamino)methyl]benzoate(365462-70-0)

Safety Data

• Hazardous Substances Data: 365462-70-0(Hazardous Substances Data)

Upstream product

• 365462-69-7 ethyl 4-{[(3-cyanophenyl)amino]methyl}-3-nitrobenzoate 
• 7439-89-6 iron 
• 19013-15-1 ethyl 4-methyl-3-nitro-benzoate 
• 96315-16-1 4-bromomethyl-3-nitrobenzoic acid ethyl ester 

Downstream Products

• 365462-88-0 ethyl 4-{[(3-cyanophenyl)amino]methyl}-3-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoate 
• 761392-41-0 ethyl 4-[({3-[amino(imino)methyl]phenyl}amino)methyl]-3-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoate 
• 781605-91-2 4-[(3-carbamimidoyl-phenylamino)-methyl]-3-[4-(4-methyl-[1,4]diazepan-1-yl)-benzoylamino]-benzoic acid 

Relevant articles and documents

Synthesis and biological activity of novel 1,2-disubstituted benzene derivatives as factor Xa inhibitors

Factor Xa (fXa) is a serine protease that plays a pivotal role in the coagulation cascade. High-throughput screening of the Yamanouchi compound library yielded lead compound 1 with the ability to inhibit fXa at micromolar concentrations. To improve its fX