3666-82-8

Basic information

• Product Name: Methyl 2-benzyl-3-oxobutanoate
• Synonyms: Methyl 2-benzyl-3-oxobutanoate
• CAS NO: 3666-82-8
• Molecular Formula: C₁₂H₁₄O₃
• Molecular Weight: 206.23776
• Mol File: 3666-82-8.mol
• Article Data: 32

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Methyl 2-benzyl-3-oxobutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-benzyl-3-oxobutanoate(3666-82-8)
• EPA Substance Registry System: Methyl 2-benzyl-3-oxobutanoate(3666-82-8)

Safety Data

• Hazardous Substances Data: 3666-82-8(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 39, p. 3271, 1974 DOI: 10.1021/jo00936a021

Upstream product

• 34284-28-1 sodium methyl acetoacetate 
• 100-44-7 benzyl chloride 
• 108-86-1 bromobenzene 
• 98837-36-6 methyl 3-hydroxy-2-methylenebutyrate 
• 67-56-1 methanol 
• 100-39-0 benzyl bromide 
• 141-97-9 ethyl acetoacetate 
• 105-45-3 acetoacetic acid methyl ester 
• 620-79-1 Ethyl 2-benzylacetoacetate 
• 100-51-6 benzyl alcohol 
• 100-52-7 benzaldehyde 
• 15768-07-7 methyl 2-benzylidene-3-oxobutanoate 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 357914-44-4 2-Benzyl-3-oxo-butyric acid 4-((E)-2-biphenyl-4-yl-vinyl)-benzyl ester 

Downstream Products

• 112701-03-8 4-benzyl-5-methyl-1,2-dihydro-3H-pyrazol-3-one 
• 78871-84-8 2-Acetyl-2-benzyl-5-oxo-hexanoic acid methyl ester 
• 1144-50-9 5-methyl-2-(1-methylethyl)cyclohexyl-3-oxo butanoate 
• 78871-92-8 1-Benzyl-4-methyl-2-oxo-cyclohex-3-enecarboxylic acid methyl ester 
• 1020850-93-4 C₁₈H₁₆O₃ 
• 51507-18-7 methyl 2-diazohydrocinnamate 
• 1180519-50-9 methyl 3-phenyl-2-acetyl-2-hydroxypropionate 
• 7316-64-5 3-methylindene-2-carboxylic acid methyl ester 
• 34225-81-5 3-methyl-1H-indene-2-carboxylic acid 
• 2550-26-7 4-Phenyl-2-butanone 
• 1425865-30-0 C₂₁H₁₇N₃O₂ 
• 37778-97-5 (S)-methyl 3-hydroxy-2-phenylpropanoate 

Relevant articles and documents

Design, Synthesis, and Structure-Activity Relationship Study of Pyrazolones as Potent Inhibitors of Pancreatic Lipase

Pancreatic lipase (PL), a key target for the prevention and treatment of obesity, plays crucial roles in the hydrolysis and absorption of in dietary fat. In this study, a series of pyrazolones was synthesized, and their inhibitory effects against PL were

Reductive Knoevenagel Condensation with the Zn-AcOH System

An efficient gram-scale one-pot approach to 2-substituted malonates and related structures is developed, starting from commercially available aldehydes and active methylene compounds. The technique combines Knoevenagel condensation with the reduction of the C=C bond in the resulting activated alkenes with the Zn-AcOH system. The relative ease with which the C=C bond reduction occurs can be traced to the accepting abilities of the substituents in the intermediate arylidene malonates.