37111-25-4

Basic information

• Product Name: 2,3-epoxypropyl propionate
• Synonyms: 2,3-epoxypropyl propionate;Oxiranemethanol propanoate;Propionic acid 2,3-epoxypropan-1-yl ester;Propionic acid glycidyl ester
• CAS NO: 37111-25-4
• Molecular Formula: C₆H₁₀O₃
• Molecular Weight: 130.1418
• EINECS: 253-354-5
• Mol File: 37111-25-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 168.6°Cat760mmHg
• Flash Point: 76.9°C
• Appearance: /
• Density: 1.099g/cm³
• Vapor Pressure: 1.61mmHg at 25°C
• Refractive Index: 1.44
• CAS DataBase Reference: 2,3-epoxypropyl propionate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-epoxypropyl propionate(37111-25-4)
• EPA Substance Registry System: 2,3-epoxypropyl propionate(37111-25-4)

Safety Data

• Hazardous Substances Data: 37111-25-4(Hazardous Substances Data)

Usage

General Description

2,3-epoxypropyl propionate is a chemical compound that is commonly used as a solvent and a reagent in various industrial and commercial applications. It is a clear, colorless liquid with a slight odor, and it is soluble in water and most organic solvents. 2,3-epoxypropyl propionate is often used in the production of resins, coatings, adhesives, and other chemical products due to its ability to react with a wide range of compounds and its high chemical stability. It is also utilized as a crosslinking agent in the manufacturing of polymers and as a key ingredient in the formulation of specialty coatings and adhesives for the automotive, aerospace, and construction industries. Additionally, it is known for its low volatility and low toxicity, making it a preferred choice in many applications where human and environmental safety are important considerations. Overall, 2,3-epoxypropyl propionate plays a crucial role in the production of various chemical products and is valued for its versatile properties and compatibility with a range of materials.

InChI:InChI=1/C6H10O3/c1-2-6(7)9-4-5-3-8-5/h5H,2-4H2,1H3

Upstream product

• 802294-64-0 propionic acid 
• 106-89-8 epichlorohydrin 
• 137-40-6 sodium proprionate 
• 556-52-5 oxiranyl-methanol 
• 79-03-8 propionyl chloride 
• 106-90-1 glycidyl acrylate 

Downstream Products

• 72845-79-5 2-oxopropyl propionate 
• 1403681-54-8 3-[4-(2-Benzyloxy-4-ethylphenoxy)-3-fluorophenyl]-5-hydroxymethyloxazolidin-2-one 

Relevant articles and documents

Regio- and chemoselective rearrangement of terminal epoxides into methyl alkyl and aryl ketones

The development of the highly active pincer-type rhodium catalyst 2 for the nucleophilic Meinwald rearrangement of functionalised terminal epoxides into methyl ketones under mild conditions is presented. An excellent regio- and chemoselectivity is obtained for the first time for aryl oxiranes.

Role of the (Acyloxy)methyl Moiety in Eliciting the Adrenergic β-Blocking Activity of 3-(Acyloxy)propanolamines

Some totally aliphatic 3-(acyloxy)propanolamines were synthesized with the aim of testing whether β-blocking activity could be obtained from this class of drugs, even in the absence of an aromatic group.The significant and, in most cases, competitive β-blocking activity shown by the compounds under examination, together with the results of a theoretical study in which their reactivity was compared with that of other adrenergic β-blocking drugs, seems to confirm a hypothesis previously advanced on the basis of knowledge about the action mechanism of adrenergic β-blocking drugs and of the results of structural studies.It was also possible to suggest some considerations about the role played by the (acyloxy)methyl portion of 3-(acyloxy)propanolamines in eliciting their adrenergic β-blocking activity.

A Convenient Synthesis of Glycidyl Esters (2,3-Epoxypropyl Alkanoates)

A novel method for synthesizing glycidyl esters (2,3-epoxypropyl alkanoates) 1 has been achieved by the sequence of the organotin phosphate catalyzed reaction of epichlorohydrin 2 with carboxylic acids and dehydrochlorination of the resulting mixture of ester chlorohydrins 3 + 4 followed by separation.