371258-91-2

Basic information

• Product Name: Ethanone, 1-[2-[(4-methoxyphenyl)methoxy]phenyl]-
• Synonyms: Ethanone,1-[2-[(4-methoxyphenyl)methoxy]phenyl];2'-(4-methoxybenzyloxy)acetophenone;1-{2-[(4-methoxybenzyl)oxy]phenyl}ethanone
• CAS NO: 371258-91-2
• Molecular Formula: C16H16O3
• Molecular Weight: 256.301
• Mol File: 371258-91-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[2-[(4-methoxyphenyl)methoxy]phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[2-[(4-methoxyphenyl)methoxy]phenyl]-(371258-91-2)
• EPA Substance Registry System: Ethanone, 1-[2-[(4-methoxyphenyl)methoxy]phenyl]-(371258-91-2)

Safety Data

• Hazardous Substances Data: 371258-91-2(Hazardous Substances Data)

Upstream product

• 118-93-4 o-hydroxyacetophenone 
• 824-94-2 p-methoxybenzyl chloride 
• 2746-25-0 p-Methoxybenzyl bromide 

Downstream Products

• 131137-81-0 1-<2-<(4-Methoxyphenyl)methoxy>phenyl>-2-<(4-methylphenyl)sulphinyl>ethanone 
• 573974-68-2 2'-(4-methoxybenzyloxy)acetophenone tosylhydrazone 
• 726180-32-1 2-hydroxy-1-[2-(4-methoxybenzyloxy)phenyl]ethanone 
• 726180-42-3 1-[2-(4-methoxybenzyloxy)phenyl]-2-methoxymethoxyethanone 
• 726180-53-6 N-{1-[2-(4-methoxybenzyloxy)phenyl]-2-methoxymethoxyvinyl}acetamide 
• 38276-96-9 (±)-trans-2-(4-methoxyphenyl)-3-methyl-2,3-dihydrobenzofuran 
• 38276-97-0 rac-cis-2-(4-methoxyphenyl)-3-methyl-2,3-dihydrobenzofuran 
• 405239-74-9 tert-butyl 2-amino-4-{1-[(benzyloxy)carbonyl]-3-piperidinyl}-6-{2-[(4-methoxybenzyl)oxy]phenyl}nicotinate 
• 118-93-4 o-hydroxyacetophenone 

Relevant articles and documents

A convenient approach for the deprotection and scavenging of the PMB group using POCl3

A convenient and high yielding approach for the deprotection and scavenging of the p-methoxybenzyl (PMB) group in PMB ethers and PMB esters was developed using POCl3 as the reagent. 4-Methoxybenzyl chloride, a starting material used for the preparation of PMB ethers and esters was regenerated in the deprotection step. This mild and selective procedure tolerates several acid sensitive functional groups. The Royal Society of Chemistry 2013.

Synthesis and structure-activity relationships of novel IKK-β inhibitors. Part 3: Orally active anti-inflammatory agents

A series of 2-amino-3-cyano-4-alkyl-6-(2-hydroxyphenyl)pyridine derivatives was synthesized and evaluated as IκB kinase β (IKK-β) inhibitors. Modification of a novel IKK-β inhibitor 1 (IKK-β IC 50=1500nM, Cell IC50=8000nM) at the 4-p

Conjugate addition to 3-arylsulfinylchromones as a synthetic route to homochiral 2-substituted chromanones: Scope and limitations

A route to homochiral 2-substituted chromanones via the diastereoselective conjugate addition of organocopper reagents to 3-(p-tolylsulfinyl)chromones has been improved and used to prepare 2,6-dimethylchromanone (S)-4 and LL-D253α methyl ether (S)-6. The attempted preparation of a 2-phenylchromanone (flavanone) using this strategy was unsuccessful due to the lability of the intermediate 2-phenyl-3-(p-tolylsulfinyl)chromanone, which underwent sulfoxide elimination at room temperature to give the corresponding 2-phenylchromone (flavone).