373384-18-0

Basic information

• Product Name: 3-(Methylsulfonyl)phenylboronic acid
• Synonyms: 3-(METHYLSULFONYL)PHENYLBORONIC ACID;3-(METHYLSULPHONYL)BENZENEBORONIC ACID;3-(METHANESULFONYL)PHENYLBORONIC ACID;3-(methylsulfonyloxy)phenylboronic acid;Boronic acid, [3-(methylsulfonyl)phenyl]- (9CI);3-(Methylsulfonyl)Phenylboroni;3-(Methylsulfonyl)phenylboronic acid ,98%;3-(Methylsulfonyl)benzeneboronic acid
• CAS NO: 373384-18-0
• Molecular Formula: C₇H₉BO₄S
• Molecular Weight: 200.01996
• Product Categories: BORONICACID;blocks;BoronicAcids;Boronic acids;Boronic Acid;Aryl;Organoborons;Boronate Ester;Potassium Trifluoroborate
• Mol File: 373384-18-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 102-110°C
• Boiling Point: 478.3 °C at 760 mmHg
• Flash Point: 243.1 °C
• Appearance: /
• Density: 1.39 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 7.11±0.10(Predicted)
• CAS DataBase Reference: 3-(Methylsulfonyl)phenylboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(Methylsulfonyl)phenylboronic acid(373384-18-0)
• EPA Substance Registry System: 3-(Methylsulfonyl)phenylboronic acid(373384-18-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• HazardClass: IRRITANT
• Hazardous Substances Data: 373384-18-0(Hazardous Substances Data)

Usage

General Description

3-(Methylsulfonyl)phenylboronic acid is a chemical compound with the formula C7H9BO4S. It is a boronic acid derivative that contains a phenyl group with a methylsulfonyl substituent. 3-(Methylsulfonyl)phenylboronic acid is used as a reagent in organic synthesis, particularly in the formation of carbon-carbon and carbon-heteroatom bonds through boronate cross-coupling reactions. It is also a valuable building block in the preparation of pharmaceuticals, agrochemicals, and materials. 3-(Methylsulfonyl)phenylboronic acid is known for its high stability and selectivity in chemical transformations, making it a useful tool in the production of complex organic compounds.

InChI:InChI=1/C7H9BO4S/c1-13(11,12)7-4-2-3-6(5-7)8(9)10/h2-5,9-10H,1H3

Downstream Products

• 936482-45-0 C₂₇H₂₉F₃N₄O₄S 
• 936482-46-1 C₂₆H₂₈F₃N₅O₄S 
• 891842-47-0 N-((5-ethoxy-2-fluoro-3-isopropoxyphenyl)(4-(3-(methylsulfonyl)phenyl)-1-trityl-1H-imidazol-2-yl)methyl)-4-(5-methyl-1,2,4-oxadiazol-3-yl)benzenamine 
• 919351-61-4 (S)-1-((3R,3aR,6S,6aS)-6-fluoro-3-hydroxy-hexahydro-furo[3,2-b]pyrrol-4-yl)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(3'-methanesulfonyl-biphenyl-4-yl)-ethylamino]-pentan-1-one 
• 1040281-01-3 8-chloro-1-[3-(methylsulfonyl)phenyl]-5,6-dihydrobenzo[f]quinazoline-3,9-diamine 
• 1045861-03-7 2,4-dichloro-6-(3-(methylsulfonyl)phenyl)pyrimidine 
• 1045861-04-8 2-chloro-4,6-bis(3-(methylsulfonyl)phenyl)pyrimidine 
• 1042443-47-9 C₂₆H₂₃Cl₂N₃O₂S 
• 1140626-73-8 ((1,3-benzothiazol-2-ylmethyl){[2-(3-methanesulfonylphenyl)-4-methyl-1,3-thiazol-5-yl]carbonyl}amino)acetic acid 
• 1207970-85-1 ethyl 3-[2-[3-(methylsulfonyl)benzyl]-1-benzothiophen-7-yl]benzoate 
• 1207970-77-1 7-chloro-4-fluoro-2-[3-(methylsulfonyl)benzyl]-1-benzothiophene 
• 1220690-46-9 5-(3-methylsulfonyl)phenyl-N-(naphthalen-2-ylmethyl)pyridin-3-amine 
• 1220690-41-4 (3-cyclopentyloxy-4-methoxybenzyl)-[5-(3-methylsulfonylphenyl)pyridin-3-yl]amine 
• 1220690-45-8 C₂₅H₂₈N₂O₅S 

Relevant articles and documents

DIPHENYL-DIHYDRO-IMIDAZOPYRIDINONES

and the pharmaceutically acceptable salts and esters thereof X, R1, R2, Y1 and Y2 are described herein inhibit the interaction of MDM2 protein with a p53-like peptide and hence have anti proliferative activity.