37482-16-9Relevant articles and documents
Synthesis of 2-azido-1,N6-etheno and 2-azido analogs of deoxyadenosine as nucleotide photoaffinity probes
Flaherty,Balse,Li,Moore,Doughty
, p. 65 - 76 (1995)
We prepared 2-azido-1,N6-etheno-2'-deoxyadenosine 5'-monophosphate (7b) by activation of the 2-thio analog 4b by two methods. In the preferred method, 4b was treated with 2,4-dinitrofluorobenzene in 50% aqueous acetonitrile, and the resultant thioether was cleaved with hydrazoic acid, yielding the 2-azido-1,N6-etheno analog 7b in 70% isolated yield. N-bromoacetamide oxidized the etheno group of 7b, giving the 2-azido analog of dAMP 9b in 78% yield.
Modification of adenine and cytosine derivatives with bromoacetaldehyde
Kayasuga,Hashimoto,Negishi,et al.
, p. 932 - 938 (2007/10/02)
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