3772-43-8

Basic information

• Product Name: Butoxycaine
• Synonyms: 2-(Diethylamino)ethyl 4-butoxybenzoate; 2-Diethylaminoethyl p-Butoxybenzoate; 3772-43-8; benzoic acid, 4-butoxy-, 2-(diethylamino)ethyl ester; Butoxycaine
• CAS NO: 3772-43-8
• Molecular Formula: C₁₇H₂₇NO₃
• Molecular Weight: 293.40118
• Mol File: 3772-43-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 395°Cat760mmHg
• Flash Point: 192.7°C
• Appearance: /
• Density: 1.009g/cm³
• Vapor Pressure: 1.89E-06mmHg at 25°C
• Refractive Index: 1.5
• CAS DataBase Reference: Butoxycaine(CAS DataBase Reference)
• NIST Chemistry Reference: Butoxycaine(3772-43-8)
• EPA Substance Registry System: Butoxycaine(3772-43-8)

Safety Data

• Hazardous Substances Data: 3772-43-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H27NO3/c1-4-7-13-20-16-10-8-15(9-11-16)17(19)21-14-12-18(5-2)6-3/h8-11H,4-7,12-14H2,1-3H3

Upstream product

• 109-89-7 diethylamine 
• 100-37-8 2-(Diethylamino)ethanol 
• 33863-86-4 4-(n-butyloxy)benzoyl chloride 
• 5198-00-5 4-butoxy-thiobenzoic acid O-ethyl ester 
• 1498-96-0 4-butoxybenzoic acid 
• 4906-25-6 methyl 4-butyloxybenzoate 
• 71-43-2 benzene 
• 39969-57-8 1-bromo-4-butoxybenzene 
• 201230-82-2 carbon monoxide 
• 47168-12-7 4-Butoxy-thiobenzoic acid O-(2-diethylamino-ethyl) ester 
• 99-76-3 methyl 4-hydroxylbenzoate 
• 15788-79-1 4-butoxy-thiobenzoic acid S-(2-diethylamino-ethyl ester) 

Relevant articles and documents

Scalable and Phosphine-Free Conversion of Alcohols to Carbon-Heteroatom Bonds through the Blue Light-Promoted Iodination Reaction

One of the fundamental and highly valuable transformations in organic chemistry is the nucleophilic substitution of alcohols. Traditionally, these reactions require strategies that employ stoichiometric hazardous reagents and are associated with difficulty in purification of the by-products. To overcome these challenges, here, we report a simple route toward the diverse conversion of alcohols via an SN2 pathway, in which blue light-promoted iodination is used to form alkyl iodide intermediates from simple unreactive alcohols. The scope of the process tolerates a range of nucleophiles to construct C-N, C-O, C-S, and C-C bonds. Furthermore, we also demonstrate that this method can be used for the preparation and late-stage functionalization of pharmaceuticals, as highlighted by the syntheses of thiocarlide, butoxycaine, and pramoxine.

Benzene C-H Etherification via Photocatalytic Hydrogen-Evolution Cross-Coupling Reaction

Aryl ethers can be constructed from the direct coupling between the benzene C-H bond and the alcohol O-H bond with the evolution of hydrogen via the synergistic merger of photocatalysis and cobalt catalysis. Utilizing the dual catalyst system consisting of 3-cyano-1-methylquinolinum photocatalyst and cobaloxime, intermolecular etherification of arenes with various alcohols and intramolecular alkoxylation of 3-phenylpropanols with formation of chromanes are accomplished. These reactions proceed at remarkably mild conditions, and the sole byproduct is equivalent hydrogen gas.

SYSTEM PROVIDING CONTROLLED DELIVERY OF GASEOUS CO FOR CARBONYLATION REACTIONS

A carbonylation system comprising at least one carbon monoxide producing chamber and at least one carbon monoxide consuming chamber forming an interconnected multi-chamber system, said interconnection allowing carbon monoxide to pass from the at least one carbon monoxide producing chamber to the at least one carbon monoxide consuming chamber, said at least one carbon monoxide producing chamber containing a reaction mixture comprising a carbon monoxide precursor and a catalyst, said at least one carbon monoxide consuming chamber being suitable for carbonylation reactions, said interconnected multi- chamber system being sealable from the surrounding atmosphere during carbonylation.