3775-29-9

Basic information

• Product Name: 2-methylenepropane-1,3-diyl diacetate
• Synonyms: 2-methylenepropane-1,3-diyl diacetate;1,3-BIS (ACETOXYISOBUTENE);1,3-Diacetoxy-2-methylenepropane;Bisacetic acid 2-methylene-1,3-propanediyl ester;Diacetic acid 2-methylene-1,3-propanediyl ester;Diacetic acid 2-methylenepropane-1,3-diyl ester;2-(acetyloxymethyl)prop-2-enyl acetate;2-(acetyloxymethyl)prop-2-enyl ethanoate
• CAS NO: 3775-29-9
• Molecular Formula: C₈H₁₂O₄
• Molecular Weight: 172.17848
• EINECS: 223-225-8
• Mol File: 3775-29-9.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 225.3°Cat760mmHg
• Flash Point: 104.8°C
• Appearance: /
• Density: 1.059g/cm³
• Vapor Pressure: 0.0871mmHg at 25°C
• Refractive Index: 1.433
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility: 28.9g/L at 20℃
• CAS DataBase Reference: 2-methylenepropane-1,3-diyl diacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methylenepropane-1,3-diyl diacetate(3775-29-9)
• EPA Substance Registry System: 2-methylenepropane-1,3-diyl diacetate(3775-29-9)

Safety Data

• Hazardous Substances Data: 3775-29-9(Hazardous Substances Data)

Usage

General Description

2-Methylenepropane-1,3-diyl diacetate is a chemical compound with the molecular formula C7H12O4. It is also known as diacetoxymethylenemethane and is commonly used as a solvent or a raw material in organic synthesis. It is a clear liquid with a fruity odor and is flammable. This chemical is primarily used in the production of pharmaceuticals, flavors, and fragrances. It is important to handle and store this chemical with care, as it can be harmful if swallowed, inhaled, or if it comes into contact with the skin. Proper protective equipment and handling procedures should be followed when working with 2-methylenepropane-1,3-diyl diacetate to ensure safety.

InChI:InChI=1/C8H12O4/c1-6(4-11-7(2)9)5-12-8(3)10/h1,4-5H2,2-3H3

Upstream product

• 52813-48-6 3-bromo-2,2-bis(bromomethyl)propanoic acid 
• 127-08-2 potassium acetate 
• 127-09-3 sodium acetate 
• 108-24-7 acetic anhydride 
• 52031-17-1 2,2-(dibromomethyl)-2-bromopropanoic acid chloride 
• 64-19-7 acetic acid 
• 1871-57-4 2-chloromethyl-3-chloroprop-1-ene 
• 115-11-7 isobutene 
• 820-71-3 methallyl acetate 
• 6946-10-7 1,3-diacetoxyacetone 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 105-70-4 2-hydroxypropane-1,3-diyl diacetate 
• 108-05-4 vinyl acetate 
• 3513-81-3 2-(Hydroxymethyl)allyl alcohol 

Downstream Products

• 115975-07-0 1-(2-Methyl-5-methylene-5,6-dihydro-4H-pyran-3-yl)-ethanone 
• 258522-25-7 (5S)-7,8,9,10-tetrahydro-2-methoxy-7-methylene-11-oxo-5,9-methanocycloocta[b]pyridine-5(6H)carboxylic acid, (1R,2S)-2-phenylcyclohexyl ester 
• 2163-42-0 2-methyl-1.3-propanediol 
• 1450880-22-4 Z-dimethyl-4’-(3-benzoyl-2,4-dioxo-pyrimidin-1-yl)-3’-(acetyloxymethyl)-but-2’-enylphosphonate 
• 1450880-23-5 Z-dimethyl-4’-(3-benzoyl-5-methyl-2,4-dioxo-pyrimidin-1-yl)-3’-(acetyloxymethyl)-but-2’-enylphosphonate 

Relevant articles and documents

METHOD FOR PRODUCING 1,3-BISACYLOXY-2-METHYLENE PROPANE

A method for producing a 1,3-bisacyloxy-2-methylenepropane represented by the following general formula (II), including reacting a carboxylic acid represented by the following general formula (I), isobutylene, and oxygen, in a liquid phase, in the presence of a catalyst containing a carrier having carried thereon palladium and a transition metal of Group 11 in the periodic table, and a catalyst activator.

METHOD FOR PRODUCING BIS-ACYLOXYLATED EXOMETHYLENE COMPOUND

A method of producing a bis-acyloxylated exomethylene compound represented by general formula (III), including reacting a monoacyloxylated exomethylene compound represented by general formula (I), a carboxylic acid represented by general formula (II), and oxygen in a liquid phase in the presence of a catalyst and optionally a solvent:

Synthetic method of huperzine A

The invention belongs to the technical field of medicine synthesis and particularly relates to a synthetic method of huperzine A. The method includes twelve steps of reactions, 1,4-dioxaspiro[4.5]decan-8-one being a raw material, so that the chemical synthesis of the huperzine A is completed at a high total yield. The method is fewer in reaction steps, is simple in operations, has high yield, is stable in intermediates and gentle in reaction conditions, and is easy to control in reactions.