378232-24-7

Basic information

• Product Name: ethyl 2-ethyl-3-[3-(hydroxyimino)-4-methoxyphenyl]propanoate
• Synonyms: ethyl 2-ethyl-3-[3-(hydroxyimino)-4-methoxyphenyl]propanoate
• CAS NO: 378232-24-7
• Molecular Weight: 279.336
• Mol File: 378232-24-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 2-ethyl-3-[3-(hydroxyimino)-4-methoxyphenyl]propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-ethyl-3-[3-(hydroxyimino)-4-methoxyphenyl]propanoate(378232-24-7)
• EPA Substance Registry System: ethyl 2-ethyl-3-[3-(hydroxyimino)-4-methoxyphenyl]propanoate(378232-24-7)

Safety Data

• Hazardous Substances Data: 378232-24-7(Hazardous Substances Data)

Upstream product

• 378232-23-6 ethyl 2-ethyl-3-(3-formyl-4-methoxyphenyl)propanoate 
• 17145-91-4 triethyl 2-ethylphosphonoacetate 
• 53618-36-3 ethyl 2-ethyl-3-(4-methoxyphenyl)acrylate 
• 123-11-5 4-methoxy-benzaldehyde 
• 378232-17-8 ethyl 2-[1-(4-methoxyphenyl)methyl]butyrate 

Downstream Products

• 378232-30-5 ethyl 2-ethyl-3-[3-[4-(trifluoromethyl)benzylaminomethyl]-4-methoxyphenyl]propanoate 
• 334015-34-8 ethyl 2-ethyl-3-[3-[4-(trifluoromethyl)benzoylaminomethyl]-4-methoxyphenyl]propanoate 
• 1310070-48-4 2-(4-methoxy-3-((4-phenethoxybenzamido)methyl)benzyl)butanoic acid 
• 1310070-47-3 2-(3-((4-(benzyloxy)benzamido)methyl)-4-methoxybenzyl)butanoic acid 
• 1000675-18-2 2-(4-methoxy-3-((2-phenylbenzamido)methyl)benzyl)butanoic acid 
• 1000675-17-1 2-(4-methoxy-3-((3-phenylbenzamido)methyl)benzyl)butanoic acid 
• 1310070-43-9 2-(4-methoxy-3-((2-phenoxybenzamido)methyl)benzyl)butanoic acid 
• 1310070-42-8 2-(4-methoxy-3-((3-phenoxybenzamido)methyl)benzyl)butanoic acid 
• 334013-94-4 2-(4-methoxy-3-((4-(trifluoromethoxy)benzamido)methyl)benzyl)butanoic acid 
• 1310070-38-2 C₃₀H₃₅NO₅ 
• 1310070-37-1 C₂₉H₃₃NO₅ 
• 1310070-36-0 C₂₈H₃₁NO₄ 
• 1310070-35-9 C₂₈H₃₁NO₄ 
• 1310070-33-7 C₂₈H₃₁NO₅ 

Relevant articles and documents

Structure-based design, synthesis, and nonalcoholic steatohepatitis (NASH)-preventive effect of phenylpropanoic acid peroxisome proliferator- activated receptor (PPAR) α-selective agonists

A series of α-ethylphenylpropanoic acid derivatives was prepared as candidate peroxisome proliferator-activated receptor (PPAR) α-selective agonists, based on our PPARα/δ dual agonist 3 as a lead compound. Structure-activity relationship studies clearly indicated that the steric bulkiness and position of the distal hydrophobic tail part are critical for PPARα agonistic activity and PPARα selectivity, as had been predicted from a molecular-modeling study. A representative compound blocked the progression of nonalcoholic steatohepatitis (NASH) in an animal model.