378759-67-2

Basic information

• Product Name: 2-Propenoic acid, 3-(2-iodophenyl)-, ethyl ester, (2E)-
• CAS NO: 378759-67-2
• Molecular Formula: C11H11IO2
• Molecular Weight: 302.112
• Mol File: 378759-67-2.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-(2-iodophenyl)-, ethyl ester, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-(2-iodophenyl)-, ethyl ester, (2E)-(378759-67-2)
• EPA Substance Registry System: 2-Propenoic acid, 3-(2-iodophenyl)-, ethyl ester, (2E)-(378759-67-2)

Safety Data

• Hazardous Substances Data: 378759-67-2(Hazardous Substances Data)

Upstream product

• 5159-41-1 2-iodobenzyl alcohol 
• 140-88-5 ethyl acrylate 
• 88-67-5 2-Iodobenzoic acid 
• 26260-02-6 2-iodobenzaldehyde 
• 16139-79-0 ethyl diphenylphosphonoacetate 
• 105-36-2 ethyl bromoacetate 
• 412272-46-9 o-iodobenzyl p-tolyl sulfone 
• 64-17-5 ethanol 
• 90276-19-0 (E)-3-(2-Iodophenyl)propenoic acid 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 

Downstream Products

• 953391-26-9 ethyl E-2-(1-pentynyl)cinnamate 
• 39993-62-9 (E)-3-(2-iodophenyl)propenal 
• 90276-19-0 (E)-3-(2-Iodophenyl)propenoic acid 
• 122951-06-8 ethyl 3-(2-iodophenyl)propanoate 
• 96606-95-0 3-(2-iodophenyl)propanoic acid 
• 1643-34-1 3-(2-iodophenyl)acrylic acid 
• 125775-12-4 3-<2-(1(Z)-pentenyl)phenyl>-2(E)-propenoic acid ethyl ester 
• 125775-13-5 3-(2-(1-Z-n-pentenyl)phenyl)-E-acrylic acid 

Relevant articles and documents

INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE - SYNTHESIS AND USE THEREOF FOR TREATMENT OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA AND LYMPHOMA

The present invention relates to new compounds of general formula I, their synthesis, their pharmaceutically acceptable salts, and their use in treatment of T-cell acute lymphoblastic leukemia and lymphoma.

Tandem Copper-Catalyzed Regioselective N-Arylation-Aza-Michael Addition: Synthesis of Tetracyclic 5 H-Benzothiazolo[3,2- a]quinazoline Derivatives

A copper-catalyzed tandem process integrating regioselective N-arylation, followed by aza-Michael addition, is disclosed using 2-aminobenzothiazoles and ortho-halo cinnamic acid congeners. This process generated diverse tetracyclic 5H-benzothiazolo[3,2-a]quinazoline derivatives in moderate to good yields. The present tandem reaction appears to proceed through concomitant ring opening of 2-aminobenzothiazole and S-arylation to give the ortho-cyanamide-substituted diaryl thioether intermediate. The thus generated intermediate likely undergoes an unprecedented Truce-Smiles-type rearrangement involving S- to N-aryl migration, followed by reformation of the thiazole ring and intramolecular aza-Michael addition to furnish the title products.

Gold catalyzed Heck-coupling of arenediazonium o-benzenedisulfonimides

Diazonium salts, and precisely arenediazonium o-benzenedisulfonimides, have been used for the first time as efficient electrophilic partners in gold catalyzed Heck-coupling reactions. The synthetic protocol was general, easy and gave the target products in satisfactory yields. Mechanistic insights revealed the fundamental roles of the o-benzenedisulfonimide anion as an electron transfer agent thath promotes a radical pathway that does not require the presence of photocatalysts or external oxidants.