380342-10-9

Basic information

• Product Name: ethyl 6-(4'-methoxyphenyl)-3-methyl-1-phenyl-1Hpyrazolo[3,4-b]pyridine-4-carboxylate
• Synonyms: ethyl 6-(4'-methoxyphenyl)-3-methyl-1-phenyl-1Hpyrazolo[3,4-b]pyridine-4-carboxylate
• CAS NO: 380342-10-9
• Molecular Weight: 387.438
• Mol File: 380342-10-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethyl 6-(4'-methoxyphenyl)-3-methyl-1-phenyl-1Hpyrazolo[3,4-b]pyridine-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 6-(4'-methoxyphenyl)-3-methyl-1-phenyl-1Hpyrazolo[3,4-b]pyridine-4-carboxylate(380342-10-9)
• EPA Substance Registry System: ethyl 6-(4'-methoxyphenyl)-3-methyl-1-phenyl-1Hpyrazolo[3,4-b]pyridine-4-carboxylate(380342-10-9)

Safety Data

• Hazardous Substances Data: 380342-10-9(Hazardous Substances Data)

Upstream product

• 617-35-6 2-oxo-propionic acid ethyl ester 
• 130626-88-9 [1-(4-Methoxy-phenyl)-meth-(E)-ylidene]-(5-methyl-2-phenyl-2H-pyrazol-3-yl)-amine 
• 1131-18-6 1-Phenyl-3-methyl-5-aminopyrazole 
• 35322-20-4 ethyl 3-(4-methoxybenzoyl)pyruvate 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 380193-14-6 C₂₁H₁₉N₅O₂ 

Relevant articles and documents

Pyrazolopyridines I: Synthesis of some pyrazolo[3,4-b]pyridine-4- carboxylates

A series of ethyl 3-methyl-1-phenyl-6-aryl-1 H-pyrazolo[3,4-b]pyridine-4- carboxylates were prepared by the reaction of 5-amino-3-methyl-1-phenyl-1 H-pyrazole with various aromatic aldehydes and ethyl pyruvate. The structure elucidation of the prepared compounds was carried out by spectroscopic techniques (mass, IR, 1H and 13C NMR).

Synthesis, in vitro evaluation, and SAR studies of a potential antichagasic 1H-pyrazolo[3,4-b]pyridine series

The development of new drugs against Trypanosoma cruzi is still required since the only two drugs currently used cause severe side effects. In this work we described the synthesis, the in vitro biological evaluation, and the SAR results of 1H-pyrazolo[3,4