3839-22-3 Usage
Description
2-Cyanobenzoic acid is an organic compound with the chemical formula C8H5NO2. It is a white crystalline solid that is soluble in water and has a molecular weight of 151.14 g/mol. It is a derivative of benzoic acid, with a cyano group (C≡N) attached to the 2nd position of the benzene ring. 2-CYANOBENZOIC ACID is known for its versatile chemical properties and is widely used in various chemical reactions and applications.
Uses
Used in Pharmaceutical Industry:
2-Cyanobenzoic acid is used as a reactant in the synthesis of T-box riboswitch antiterminator RNA-binding oxazolidinone derivatives, which have potential applications in the development of new drugs targeting RNA-based regulatory mechanisms in various diseases.
Used in Chemical Industry:
2-Cyanobenzoic acid is used as a reactant in the synthesis of Benzoate modified β-cyclodextrin derivatives. These derivatives have potential applications in various fields, such as drug delivery, supramolecular chemistry, and the development of new materials with unique properties.
Used in Pharmaceutical Industry:
2-Cyanobenzoic acid is used as a reactant in the synthesis of Pyrrolo[1,2-f]triazines, which are potential JAK2 inhibitors. JAK2 inhibitors have potential applications in the treatment of various inflammatory and autoimmune diseases, as well as certain types of cancer.
Used in Chemical Industry:
2-Cyanobenzoic acid is used as a reactant involved in decarboxylation, decarboxylative halogenation, and protodecarboxylation reactions. These reactions are important in the synthesis of various organic compounds and the development of new chemical processes.
Used in Chemical Industry:
2-Cyanobenzoic acid may be used to synthesize phthalamidine, a compound with potential applications in various fields, such as pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 3839-22-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,8,3 and 9 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 3839-22:
(6*3)+(5*8)+(4*3)+(3*9)+(2*2)+(1*2)=103
103 % 10 = 3
So 3839-22-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H5NO2/c9-5-6-3-1-2-4-7(6)8(10)11/h1-4H,(H,10,11)/p-1
3839-22-3Relevant articles and documents
Base mediated spirocyclization of quinazoline: One-step synthesis of spiro-isoindolinone dihydroquinazolinones
Jinkala, Rajesh,Madhu Babu, M. V.,Murthy, V. Narayana,Nikumbh, Satish P.,Raghunadh, Akula,Rama Mohan, Hindupur,Siddaiah, Vidavalur,Tadiparthi, Krishnaji,Venkateshwarlu, Rapolu
, p. 9486 - 9491 (2020)
A novel approach for the spiro-isoindolinone dihydroquinazolinones has been demonstrated from 2-aminobenzamide and 2-cyanomethyl benzoate in the presence of KHMDS as a base to get moderate yields. The reaction has been screened in various bases followed by solvents and a gram scale reaction has also been executed under the given conditions. Based on the controlled experiments a plausible reaction mechanism has been proposed. Further the substrate scope of this reaction has also been studied.
o-Cyanobenzoate: A Recyclable and Reusable Stereo-directing Group for β-O-Glycosylation via Pd(0)-catalyzed Ferrier Rearrangement
Das, Pradip,Kumar, Amit,Rahaman Molla, Mosidur,Thakur, Rima
supporting information, (2022/01/06)
Inner sphere Tsuji-Trost reaction has found recent application for β-selective Ferrier rearrangement of glycal substrates with alcohol nucleophiles. Herein, we report an efficient and stereoselective synthesis of 2,3-dideoxy-β-O-glycosides from C3-(o-cyan
Cleavage of Carboxylic Esters by Aluminum and Iodine
Sang, Dayong,Yue, Huaxin,Fu, Yang,Tian, Juan
, p. 4254 - 4261 (2021/03/09)
A one-pot procedure for deprotecting carboxylic esters under nonhydrolytic conditions is described. Typical alkyl carboxylates are readily deblocked to the carboxylic acids by the action of aluminum powder and iodine in anhydrous acetonitrile. Cleavage of lactones affords the corresponding ω-iodoalkylcarboxylic acids. Aryl acetylates undergo deacetylation with the participation of the neighboring group. This method enables the selective cleavage of alkyl carboxylic esters in the presence of aryl esters.
