3867-18-3

Basic information

• Product Name: 2-AMINOSTYRENE
• Synonyms: 2-AMINOSTYRENE;2-Styrenamine;o-Vinylaniline;2-vinylbenzenamine;2-ethenylaniline
• CAS NO: 3867-18-3
• Molecular Formula: C₈H₉N
• Molecular Weight: 119.16376
• Mol File: 3867-18-3.mol
• Article Data: 81

Chemical Properties

• Boiling Point: 212.46°C (rough estimate)
• Flash Point: 93.84 °C
• Appearance: /
• Density: 1.0181
• Refractive Index: 1.6124
• Storage Temp.: 2-8°C(protect from light)
• PKA: 3.86±0.10(Predicted)
• CAS DataBase Reference: 2-AMINOSTYRENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINOSTYRENE(3867-18-3)
• EPA Substance Registry System: 2-AMINOSTYRENE(3867-18-3)

Safety Data

• Hazardous Substances Data: 3867-18-3(Hazardous Substances Data)

Usage

Description

2-Aminostyrene, also known as 2-Vinylaniline, is an organic compound with the molecular formula C8H9N. It is a versatile building block in the synthesis of various organic molecules and has attracted significant attention due to its potential applications in different fields.

Uses

Used in Pharmaceutical Industry:
2-Aminostyrene is used as a key intermediate in the synthesis of cyclopeptides, such as solomonamides, which are considered potential antitumor agents. These cyclopeptides have shown promising results in inhibiting the growth of cancer cells and are being investigated for their potential use in cancer treatment.
Used in Chemical Synthesis:
2-Aminostyrene serves as a valuable building block in the synthesis of various organic molecules, including pharmaceuticals, dyes, and other specialty chemicals. Its unique structure allows for a wide range of chemical reactions, making it a useful compound in the development of new materials and products.

Upstream product

• 917-54-4 methyllithium 
• 529-23-7 o-aminobenzaldehyde 
• 579-71-5 2-nitrostyrene 
• 615-43-0 2-iodophenylamine 
• 7486-35-3 tri-n-butyl(vinyl)tin 
• 92988-08-4 trivinylboroxin 
• 2039-87-4 2-chlorostyrene 
• 33768-43-3 N-(2-formylphenyl)benzamide 
• 175846-71-6 N-(2-vinyl-phenyl)benzamide 
• 201024-81-9 C,N-diphenylnitrone 
• 100-52-7 benzaldehyde 
• 98-82-8 Isopropylbenzene 
• 5339-85-5 2-aminophenethyl alcohol 
• 2065-66-9 methyl-triphenylphosphonium iodide 

Downstream Products

• 29124-68-3 N-(2-vinylphenyl)acetamide 
• 175846-71-6 N-(2-vinyl-phenyl)benzamide 
• 143879-49-6 2,2,2-trifluoro-N-(2-vinylphenyl)acetamide 
• 95-20-5 2-methyl-1H-indole 
• 91-63-4 2-methylquinoline 
• 1780-19-4 1,2,3,4-tetrahydro-2-methylquinoline 
• 632326-64-8 pent-4-enoic acid (2-vinylphenyl)amide 
• 360059-87-6 2-(N-nitrobenzenesulfonyl)aminostyrene 
• 875897-55-5 (E)-1-phenyl-N-(2-vinylphenyl)methanimine 
• 1007873-41-7 C₂₉H₃₇N₃O₂ 
• 1395059-84-3 2-iodo-N-methyl-N-(2-vinylphenyl)benzamide 
• 1395059-83-2 2-iodo-N-(2-vinylphenyl)benzamide 
• 256-96-2 dibenzoazepine 
• 71907-71-6 1-(dimethoxymethyl)-2-aminobenzene 

Relevant articles and documents

BN Polystyrenes: Emerging Optical Materials and Versatile Intermediates

BN polystyrenes are an emerging class of polyolefins functionalized with aromatic side chains in which at least one CC bond is replaced with a BN bond. This class of structures exhibits unusual photophysical properties relative to organic polymers. BN pol

Synthesis of triphenylarsonium [11C]methylide, a new 11C-precursor. Application in the preparation of [2-11C]indole

The synthesis of the new and highly reactive 11C-precursor triphenylarsonium [11C]methylide 1 and its conversion into [2-11C]indole 6 is described. [11C]Methyltriphenylarsonium iodide 4 was prepared by quaterniz

In-situ facile synthesis novel N-doped thin graphene layer encapsulated Pd@N/C catalyst for semi-hydrogenation of alkynes

Transition metal-catalyzed semi-hydrogenation of alkynes has become one of the most popular methods for alkene synthesis. Specifically, the noble metal Pd, Rh, and Ru-based heterogeneous catalysts have been widely studied and utilized in both academia and industry. But the supported noble metal catalysts are generally suffering from leaching or aggregation during harsh reaction conditions, which resulting low catalytic reactivity and stability. Herein, we reported the facile synthesis of nitrogen doped graphene encapsulated Pd catalyst and its application in the chemo-selective semi-hydrogenation of alkynes. The graphene layer served as “bulletproof” over the active Pd Nano metal species, which was confirmed by X-ray and TEM analysis, enhanced the catalytic stability during the reaction conditions. The optimized prepared Pd@N/C catalyst showed excellent efficiency in semi-hydrogenation of phenylacetylene and other types of alkynes with un-functionalized or functionalized substituents, including the hydrogenation sensitive functional groups (NO2, ester, and halogen).

Directing-group-assisted markovnikov-selective hydrothiolation of styrenes with thiols by photoredox/cobalt catalysis

In contrast with the well-developed radical thiol-ene reaction to access anti-Markovnikov-type products, the research on the catalytic Markovnikov-selective hydrothiolation of alkenes is very restricted. Because of the catalyst poisoning of metal catalysts by organosulfur compounds, limited examples of transition-metal-catalyzed thiol-ene reactions have been reported. However, in this work, a directing-group-assisted hydrothiolation of styrenes with thiols by photoredox/cobalt catalysis is found to proceed smoothly to afford Markovnikov-type sulfides with excellent regioselectivity.

Uncovering New Excited State Photochemical Reactivity by Altering the Course of the de Mayo Reaction

An unprecedented and previously unknown photochemical reactivity of 1,3-dicarbonyl compounds is observed with amino-alkenes leading to dihydropyrans. This novel photochemical reactivity changes the established paradigm related to the De Mayo reaction between 1,3-dicarbonyl compounds and alkenes. This new reaction allows convenient access to the Marmycin core in a single step from commercially available reactants. The origin and scope of this new photoreaction is detailed with preliminary photophysical and mechanistic investigations.