38775-52-9

Basic information

• Product Name: (4-(4-Ethoxycarbonylmethoxybenzenesulfonyl)phenoxy)acetic acid ethyl ester
• CAS NO: 38775-52-9
• Molecular Formula: C₂₀H₂₂O₈S
• Molecular Weight: 422.456
• Mol File: 38775-52-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (4-(4-Ethoxycarbonylmethoxybenzenesulfonyl)phenoxy)acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-(4-Ethoxycarbonylmethoxybenzenesulfonyl)phenoxy)acetic acid ethyl ester(38775-52-9)
• EPA Substance Registry System: (4-(4-Ethoxycarbonylmethoxybenzenesulfonyl)phenoxy)acetic acid ethyl ester(38775-52-9)

Safety Data

• Hazardous Substances Data: 38775-52-9(Hazardous Substances Data)

Usage

Description

(4-(4-Ethoxycarbonylmethoxybenzenesulfonyl)phenoxy)acetic acid ethyl ester is a complex organic compound belonging to the ester family, characterized by an ethyl ester functional group, a sulfonamide group, and a phenoxyacetic acid moiety. Its intricate molecular structure and chemical properties render it a promising candidate for biomedical applications and pharmaceutical research.

Uses

Used in Pharmaceutical Research:
(4-(4-Ethoxycarbonylmethoxybenzenesulfonyl)phenoxy)acetic acid ethyl ester is used as a research compound for the development of new drugs, given its unique molecular structure and chemical properties. It holds potential for contributing to the advancement of medical treatments for various conditions.
Used in Biomedical Applications:
In the biomedical field, (4-(4-Ethoxycarbonylmethoxybenzenesulfonyl)phenoxy)acetic acid ethyl ester is utilized as a component in the design and synthesis of novel therapeutic agents. Its diverse functional groups may offer specific interactions with biological targets, which could be leveraged to address unmet medical needs.
Further studies and evaluations are necessary to fully explore the potential uses and effects of this compound, ensuring its safe and effective application in the development of new pharmaceuticals and biomedical technologies.

Upstream product

• 80-09-1 4,4'-sulfonediphenol 
• 105-39-5 chloroacetic acid ethyl ester 
• 2664-63-3 4,4'-Thiodiphenol 

Downstream Products

• 123798-91-4 (4-{4-[1-(2,6-Dichloro-phenyl)-meth-(E)-ylidene-hydrazinocarbonylmethoxy]-benzenesulfonyl}-phenoxy)-acetic acid [1-(2,6-dichloro-phenyl)-meth-(E)-ylidene]-hydrazide 
• 123827-14-5 (4-{4-[1-(4-Hydroxy-3-methoxy-phenyl)-meth-(E)-ylidene-hydrazinocarbonylmethoxy]-benzenesulfonyl}-phenoxy)-acetic acid [1-(4-hydroxy-3-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide 
• 123798-90-3 (4-{4-[1-(2,4-Dichloro-phenyl)-meth-(E)-ylidene-hydrazinocarbonylmethoxy]-benzenesulfonyl}-phenoxy)-acetic acid [1-(2,4-dichloro-phenyl)-meth-(E)-ylidene]-hydrazide 

Relevant articles and documents

Macrocyclic sulfone derivatives: Synthesis, characterization, in vitro biological evaluation and molecular docking

An artificial series of macrocycles based on 4,4′-sulfonyldiphenol intermediate was synthesized using a multistep procedure involving oxidation of bisphenol sulfide, etherification of phenolic hydroxyl groups, and final ring closure with different diamines. Different chemical species having aromatic, heteroaromatic, and aliphatic characters were incorporated into macrocyclic frameworks in the final step of ring closure. This simple and easily executable synthetic strategy was applied to synthesize 15 macrocycles (5a-o) in excellent yields. Characterization of the synthesized products was achieved through well-known modern spectroscopic techniques such as IR, NMR, and Mass. Macrocycles 5m and 5n were found to show significant AChE inhibition with IC50 values of 76.9 ± 0.24 and 71.2 ± 0.77 μM, respectively. Macrocycle 5n was also found to be an active inhibitor of butyrylcholinesterase (BChE) with IC50 score of 55.3 ± 0.54 μM. Among others, macrocycle 5l cyclized with o-phenylenediamine demonstrated moderate inhibition with IC50 value of 81.1 ± 0.54 μM. Increasing interest in studying interactions of macrocycles with different enzymatic targets compelled us to design and synthesize sulfone-based macrocycles that might prove as highly potent class of biologically active compounds.

Studies on 2-azetidinones. Part I. Preparation and antimicrobial activity of p,p'-bis(3-chloro-4-aryl-2-azetidinon-1- ylcarbamoylmethoxy)diphenylsulphones

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