38982-56-8

Basic information

• Product Name: Methyl 6-O-Trityl-2,3,4-tri-O-acetyl-α-D-galactopyranoside
• Synonyms: Methyl 2,3,4-tri-O-acetyl-6-O-trityl-a-D-galactopyranoside;Methyl 2,3,4-tri-O-acetyl-6-O-trityl-α-D-galactopyranoside;2,3,4-Triacetyl-6-trityl-α-methylgalactoside;Methyl 6-O-(Triphenylmethyl)-α-D-galactopyranoside Triacetate;Methyl 6-O-Trityl-2,3,4-tri-O-acetyl-α-D-galactopyranoside;2,3,4-Triacetyl-6-trityl-a-methylgalactoside;Methyl 6-O-(Triphenylmethyl)-a-D-galactopyranoside Triacetate;Methyl 6-O-Trityl-2,3,4-tri-O-acetyl-a-D-galactopyranoside
• CAS NO: 38982-56-8
• Molecular Formula: C₃₂H₃₄O₉
• Molecular Weight: 562.612
• Product Categories: Carbohydrates & Derivatives;Carbohydrates;13C & 2H Sugars
• Mol File: 38982-56-8.mol
• Article Data: 15

Chemical Properties

• Melting Point: 177-182°C
• Boiling Point: 612.213°C at 760 mmHg
• Flash Point: 255.014°C
• Appearance: /
• Density: 1.256g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.583
• Storage Temp.: ?20°C
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Methanol
• CAS DataBase Reference: Methyl 6-O-Trityl-2,3,4-tri-O-acetyl-α-D-galactopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 6-O-Trityl-2,3,4-tri-O-acetyl-α-D-galactopyranoside(38982-56-8)
• EPA Substance Registry System: Methyl 6-O-Trityl-2,3,4-tri-O-acetyl-α-D-galactopyranoside(38982-56-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 38982-56-8(Hazardous Substances Data)

Usage

Description

Methyl 6-O-Trityl-2,3,4-tri-O-acetyl-α-D-galactopyranoside, with the CAS number 38982-56-8, is a white solid compound that plays a significant role in organic synthesis. It is a derivative of α-D-galactopyranoside, a monosaccharide commonly found in various biological systems, and is modified with a trityl group and acetyl groups to enhance its reactivity and stability in chemical reactions.

Uses

Used in Organic Synthesis:
Methyl 6-O-Trityl-2,3,4-tri-O-acetyl-α-D-galactopyranoside is used as an intermediate in organic synthesis for the preparation of various complex organic molecules. Its unique structure, featuring the trityl group and acetyl groups, provides a versatile platform for further functionalization and modification, making it a valuable compound in the synthesis of pharmaceuticals, natural products, and other bioactive molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Methyl 6-O-Trityl-2,3,4-tri-O-acetyl-α-D-galactopyranoside is used as a key building block for the development of novel drugs targeting various diseases. Its ability to be modified and functionalized allows for the creation of new drug candidates with improved pharmacological properties, such as enhanced bioavailability, selectivity, and reduced side effects.
Used in Chemical Research:
Methyl 6-O-Trityl-2,3,4-tri-O-acetyl-α-D-galactopyranoside is also utilized in chemical research as a model compound for studying the reactivity and properties of similar carbohydrate derivatives. This helps researchers gain a deeper understanding of the fundamental chemical processes involved in carbohydrate chemistry and enables the development of new synthetic strategies and methodologies.
Used in Material Science:
In the field of material science, Methyl 6-O-Trityl-2,3,4-tri-O-acetyl-α-D-galactopyranoside can be employed as a component in the design and synthesis of advanced materials with specific properties, such as improved mechanical strength, thermal stability, or biocompatibility. Its unique structure and functional groups can be exploited to create novel materials with tailored properties for various applications, including biomedical, electronic, and environmental fields.

InChI:InChI=1/C32H34O9/c1-21(33)38-28-27(41-31(36-4)30(40-23(3)35)29(28)39-22(2)34)20-37-32(24-14-8-5-9-15-24,25-16-10-6-11-17-25)26-18-12-7-13-19-26/h5-19,27-31H,20H2,1-4H3/t27?,28-,29?,30?,31-/m0/s1

Upstream product

• 76-83-5 trityl chloride 
• 108-24-7 acetic anhydride 
• 617-04-9 (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3,4,5-triol 
• 29411-57-2 methyl-α-D-altropyranoside 
• 18311-26-7 methyl 6-O-trityl-α-D-glucopyranoside 
• 604-70-6 Acetic acid (2R,3R,4S,5R,6S)-3,5-diacetoxy-2-acetoxymethyl-6-methoxy-tetrahydro-pyran-4-yl ester 
• 97-30-3 methyl-alpha-D-glucopyranoside 
• 3458-28-4 D-Mannose 
• 20231-36-1 methyl 6-O-trityl-α-D-mannopyranoside 
• 596-43-0 bromo-triphenyl-methane 
• 3396-99-4 methyl α-D-galactopyranoside 
• 18311-26-7 methyl 6-O-triphenylmethyl-α-D-galactopyranoside 

Downstream Products

• 6087-46-3 methyl 2,3,4-tri-O-acetyl-6-chloro-6-deoxy-α-D-glucopyranoside 
• 7432-72-6 Methyl 2,3,4-tri-O-acetyl-α-D-galactopyranoside 
• 87924-29-6 methyl 2,3,6-tri-O-acetyl-α-D-galactopyranoside 
• 6639-43-6 2,2,2-triphenylacetonitrile 
• 76951-67-2 methyl 2,3,4-tri-O-acetyl-6-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-α-D-mannopyranoside 
• 7432-72-6 methyl 2,3,4-tri-O-acetyl-α-D-mannopyranoside 
• 1726-94-9 trityl isothiocyanate 
• 127066-73-3 methyl 2,3,4-tri-O-acetyl-6-O-(3,4,6-tri-O-acetyl-2-O-methyl-α-D-glucopyranosyl)-α-D-glucopyranoside 
• 604-70-6 Acetic acid (2R,3R,4S,5R,6S)-3,5-diacetoxy-2-acetoxymethyl-6-methoxy-tetrahydro-pyran-4-yl ester 
• 135644-27-8 methyl 2,3,4-tri-O-acetyl-6-O-(3,4-di-O-acetyl-2-O-benzyl-β-L-arabinopyranosyl)-α-D-glucopyranoside 
• 130052-62-9 methyl 2,3,4-tri-O-acetyl-6-O-(3,4,6-tri-O-acetyl-2-O-benzyl-α-D-galactopyranosyl)-α-D-glucopyranoside 
• 130052-67-4 Acetic acid (2R,3S,4S,5R,6S)-3-acetoxy-2-acetoxymethyl-5-benzyloxy-6-isothiocyanato-tetrahydro-pyran-4-yl ester 
• 59184-24-6 methyl O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-(1->6)-2,3,4-tri-O-acetyl-α-D-glucopyranoside 
• 122564-52-7 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl isothiocyanate 

Relevant articles and documents

Visible-Light-Mediated, Chemo- and Stereoselective Radical Process for the Synthesis of C-Glycoamino Acids

An approach for efficient synthesis of C-glycosyl amino acids is described. Different from typical photoredox-catalyzed reactions of imines, the new process follows a pathway in which α-imino esters serve as electrophiles in chemoselective addition reactions with nucleophilic glycosyl radicals. The process is highlighted by the mild nature of the reaction conditions, the highly stereoselectivity attending C-C bond formation, and its applicability to C-glycosylations using both armed and disarmed pentose and hexose derivatives.

Diazepinium perchlorate: a neutral catalyst for mild, solvent-free acetylation of carbohydrates and other substances

Diazepinium perchlorate, an essentially neutral organic salt possessing excellent stability, has been found to be well suited for the acetylation of free as well as partially protected sugars, phenols, thiophenols, thiols and other alcohols as well as amines. The diazepinium perchlorate-catalyzed acetylation is mild, organic and solvent-free and leaves acid sensitive protecting groups such as TBDMS/TBDPS/Tr ethers and isopropylidene/benzylidene acetals present on a substrate unaffected. Regioselective hydroxyl protection in partially protected carbohydrate derivatives/polyhydroxylic compounds was possible and was proved to be a convenient time-saving alternative to the conventional synthesis of such compounds. Easy preparation of the catalyst, mild reaction conditions and an environmentally benign protocol are some of the notable features of this reaction. The results obtained on the acetylation of phenols and thiophenols could be rationalized through their local nucleophilicity index obtained from DFT calculations.

Design, synthesis and antifibrotic activities of carbohydrate-modified 1-(substituted aryl)-5-trifluoromethyl-2(1H) pyridones

Pirfenidone, a pyridone compound, is an effective and novel antifibrotic agent. In this article, we describe the design, synthesis and activity evaluation of novel antifibrotic agents, 1-(substituted aryl)-5-trifluoromethyl- 2(1H) pyridones modified with