3923-51-1Relevant articles and documents
Unexpected regioselectivity in the attack of vinyl Grignard reagents to bis(2-benzothiazolyl) ketone
Boga, Carla,Forlani, Luciano,Todesco, Paolo E.
, p. 4845 - 4848 (1997)
The addition of vinyl Grignard reagents to bis(2-benzothiazolyl) ketone affords the unexpected O-alkylation products in very high yields.
Ligand-free (: Z)-selective transfer semihydrogenation of alkynes catalyzed by in situ generated oxidizable copper nanoparticles
Grela, Karol,Kusy, Rafa?
supporting information, p. 5494 - 5502 (2021/08/16)
Herein, we present (Z)-selective transfer semihydrogenation of alkynes based on in situ generated CuNPs in the presence of hydrogen donors, such as ammonia-borane and a green protic solvent. This environmentally friendly method is characterized by operational simplicity combined with high stereo- and chemoselectivity and functional group compatibility. Auto-oxidation of CuNPs after the completion of a semihydrogenation reaction results in the formation of a water-soluble ammonia complex, so that the catalyst may be reused several times by simple phase-separation with no need for any special regeneration processes. Formed NH4B(OR)4 can be easily transformed back into ammonia-borane or into boric acid. In addition, a one-pot tandem sequence involving a Suzuki reaction followed by semihydrogenation was presented, which allows minimization of chemical waste production.
Synthesis of 1-Tri(di)fluoromethyl 1,4-Diketones Enabled by Radical Brook Rearrangement
Chen, Xiang,Liu, Shanshan,Shen, Xiao,Zhang, Jianjun,Zhu, Zhihong
supporting information, p. 4927 - 4931 (2021/09/30)
Herein, we disclose the first and simple one-pot-two-step process to the synthesis of 1-difluoromethyl 1,4-diketones, through Mn-catalyzed radical Brook rearrangement. The methodology is also amenable to the synthesis of 1-trifluoromethyl 1,4-diketones. T