395683-14-4

Basic information

• Product Name: 2H-Pyrrol-2-one, 1,5-dihydro-3-(4-methylphenyl)-4-[4-(methylsulfonyl)phenyl]-1-propyl-
• CAS NO: 395683-14-4
• Molecular Formula: C21H23NO3S
• Molecular Weight: 369.485
• Mol File: 395683-14-4.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 2H-Pyrrol-2-one, 1,5-dihydro-3-(4-methylphenyl)-4-[4-(methylsulfonyl)phenyl]-1-propyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyrrol-2-one, 1,5-dihydro-3-(4-methylphenyl)-4-[4-(methylsulfonyl)phenyl]-1-propyl-(395683-14-4)
• EPA Substance Registry System: 2H-Pyrrol-2-one, 1,5-dihydro-3-(4-methylphenyl)-4-[4-(methylsulfonyl)phenyl]-1-propyl-(395683-14-4)

Safety Data

• Hazardous Substances Data: 395683-14-4(Hazardous Substances Data)

Usage

General Description

The chemical compound 2H-Pyrrol-2-one, 1,5-dihydro-3-(4-methylphenyl)-4-[4-(methylsulfonyl)phenyl]-1-propyl- is a complex organic compound with a pyrrolone ring structure and a combination of methyl, methylsulfonyl, and phenyl functional groups. It is a white to off-white crystalline solid that is insoluble in water but soluble in organic solvents. 2H-Pyrrol-2-one, 1,5-dihydro-3-(4-methylphenyl)-4-[4-(methylsulfonyl)phenyl]-1-propyl- has potential applications in pharmaceuticals, agrochemicals, and material science due to its unique structural and chemical properties. It may also have biological activity and is a subject of study in medicinal chemistry and other research fields.

Upstream product

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Relevant articles and documents

Pyrrole compound, a preparation method and uses thereof

The invention relates to a pyrrole compound, a preparation method and uses thereof, particularly to 4-(4-(methylsulfonyl)phenyl-1-propyl-3-(p-tolyl)-1H-pyrrole-2-ol (represented by a formula C) or a pharmaceutically acceptable salt thereof, a preparation

Preparation method of imrecoxib

The invention provides a preparation method of imrecoxib. The preparation method of the imrecoxib comprises the steps that alpha-n-propylamino-4-methyl sulfonate acetophenone (II) and 4-methyl phenylacetate (III) are used as main raw materials, amidation

Synthetic method of imrecoxib

The invention discloses a synthetic method of imrecoxib. The synthetic method comprises the following steps: allowing (E)-1-p-methanesulfonylphenyl-1-nitro-2-p-tolylethylene and ethyl isocyanoacetateto undergo a condensation and cyclization reaction in a system containing an alkali reagent and a solvent; allowing the obtained 3-p-methylphenyl-4-p-methylsulfonylphenylpyrrole-2-carboxylate to undergo a reducing reaction at -78 DEG C in a system containing a reducing reagent and a solvent; allowing the obtained 3-p-methylphenyl-4-p-methylsulfonylphenylpyrrole-2-carbaldehyde to undergo an oxidation reaction in a system containing a hydrogen peroxide solution and a solvent; and allowing the obtained 3-p-methylphenyl-4-p-methylsulfonylphenyl-3-pyrrolidin-2-one and 1-halopropane or a hydrocarbonpropyl sulfonate derivative to undergo a substitution reaction in a system containing an alkali reagent and a solvent to obtain the imrecoxib. The synthetic method of the imrecoxib has the beneficialeffects that the reaction steps are simplified and optimized and the process is simple in operation, thereby being helpful to reduce cost; reaction impurities are less and controllable, so greennessand environment-friendliness are embodied; and initial raw materials and the used reagents are easily available.