39571-37-4

Basic information

• Product Name: tert-Butyl [(1S)-1-(hydrazinocarbonyl)-2-methylbutyl]carbamate
• Synonyms: tert-Butyl [(1S)-1-(hydrazinocarbonyl)-2-methylbutyl]carbamate;tert-butyl N-[(1S,2S)-1-(hydrazinecarbonyl)-2-methylbutyl]carbamate
• CAS NO: 39571-37-4
• Molecular Formula: C₁₁H₂₃N₃O₃
• Molecular Weight: 245.31862
• Mol File: 39571-37-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: tert-Butyl [(1S)-1-(hydrazinocarbonyl)-2-methylbutyl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl [(1S)-1-(hydrazinocarbonyl)-2-methylbutyl]carbamate(39571-37-4)
• EPA Substance Registry System: tert-Butyl [(1S)-1-(hydrazinocarbonyl)-2-methylbutyl]carbamate(39571-37-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 39571-37-4(Hazardous Substances Data)

Upstream product

• 13139-16-7 N-(tert-butyloxycarbonyl)-L-isoleucine 
• 110694-60-5 (2S,3S)-N-(tert-butoxycarbonyl)isoleucine ethyl ester 
• 17901-01-8 N-(tert-butoxycarbonyl)isoleucine methyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 2577-46-0 L-isoleucine methyl ester 
• 13139-16-7 N-tert-butyloxy-isoleucine 

Downstream Products

• 39570-67-7 N'-((2S,3S)-2-tert-Butoxycarbonylamino-3-methyl-pentanoyl)-hydrazinecarboxylic acid 4-nitro-phenyl ester 
• 1262482-84-7 C₂₆H₄₀N₄O₆ 

Relevant articles and documents

Anti-tumor compound of targeting Neddylation path

The invention discloses an anti-tumor compound of a targeting Neddylation path. The compound can be represented by a structural formula shown as a general formula I, a general formula II, a general formula III, a general formula IV, a general formula V, a general formula VI or a general formula VII. The compound provided by the invention has good anti-tumor activity; a plurality of compounds are close to a positive control drug MLN4924 and can be used as the good anti-tumor compound. The compound and a composition, provided by the invention, can be used with other drugs to provide combined therapy, and the other drugs can form a part of the same composition or can be used as different components for drug administration at the same time or at different time.

Synthesis and antiviral evaluation of C-4-hydrazide derivatives of 2′,3′-dideoxycytidine

Syntheses of three hitherto unknown derivatives of 2′,3′-dideoxycytidine, namely C-4-(salicylic hydrazide)-ddC, C-4-(N-butyloxycarbonyl-isoleucine hydrazide)-ddC and its N-unprotected chlorhydrate salt have been carried out. These compounds do not induce inhibition of HIV-1 replication in cell culture experiments. Nevertheless, the modifications on the base moiety increased in all cases the lipophilicity of the parent molecule with an acceptable water solubility compared to ddC.