39640-02-3Relevant articles and documents
N-substituted piperazines
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Page/Page column 11, (2010/11/25)
Novel N-alkyl substituted piperazines have been discovered, which are useful as insecticides or fungicides. Such compounds are of Formula (I) wherein X, Y, R1 and R2 are as defined herein.
Dialkylaminoacetonitrile Derivatives as Amide Synthons. A One-Pot Preparation of Heteroaryl Amides via a Strategy of Sequential SNAr Substitution and Oxidation
Zhang, Zhongxing,Yin, Zhiwei,Kadow, John F.,Meanwell, Nicholas A.,Wang, Tao
, p. 1360 - 1363 (2007/10/03)
Dialkylamino acetonitrile derivatives were utilized as alternative to cyanohydrin synthons for preparation of the corresponding heteroaryl dialkyl amides via a strategy of sequential base-mediated coupling and oxidation. The most advantageous oxidant, NiO2-H2O, can readily oxidize 2-substituted aminoacetonitriles to the corresponding amides under both basic and neutral conditions by forming cyanohydrins in situ.
A NOVEL SYNTHESIS OF PYRIDINECARBOXYLIC ACID PIPERAZIDES
Budai, Z.,Mezei, T.,Lay, A.
, p. 241 - 246 (2007/10/02)
N-Substituted piperazides of pyridinecarboxylic acids were synthesized in the following way: the pyridinecarboxylic acids were converted into (alkoxy-formic acid-pyridinecarboxylic acid) mixed anhydrides by means of alkyl chloroformates, and these were th