39810-46-3

Basic information

• Product Name: N-phenyl-2-thiophenesulfonamide
• Synonyms: N-phenyl-2-thiophenesulfonamide
• CAS NO: 39810-46-3
• Molecular Formula: C₁₀H₉NO₂S₂
• Molecular Weight: 239.31396
• Mol File: 39810-46-3.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-phenyl-2-thiophenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenyl-2-thiophenesulfonamide(39810-46-3)
• EPA Substance Registry System: N-phenyl-2-thiophenesulfonamide(39810-46-3)

Safety Data

• Hazardous Substances Data: 39810-46-3(Hazardous Substances Data)

Upstream product

• 16629-19-9 thiophene-2-sulfonyl chloride 
• 62-53-3 aniline 
• 382-99-0 thiophene-2-sulfonyl fluoride 
• 66003-76-7 Diphenyliodonium triflate 
• 38945-01-6 sodium thiophene-2-sulphinate 
• 98-95-3 nitrobenzene 
• 6339-87-3 2-thiophensulfonamide 
• 873-55-2 sodium benzenesulfonate 
• 6165-68-0 thiophene boronic acid 

Downstream Products

• 1313758-86-9 5-(4-nitrophenyl)thiophene-2-sulfonic acid phenylamide 
• 1599476-70-6 N-(1-allyl-5-methyl-1H-indol-2-yl)-N-(2-iodophenyl)thiophene-2-sulfonamide 

Relevant articles and documents

Copper-Catalyzed Aminoarylation of Alkenes via Aminyl Radical Addition and Aryl Migration

We describe a new strategy for aminoarylation of alkenes by copper-catalyzed smiles rearrangement using O-benzoylhydroxylamines as the amine reagent. This method affords various β-amino amide derivatives possessing a quaternary carbon center with wide functional group tolerance and high regioselectivity. The mechanistic studies indicate that the transformation can involve aminyl radical intermediates under acid-free condition.

Synthesis of N-phenylsulfonamide derivatives and investigation of some esterase enzymes inhibiting properties

In this study, synthesis of nine N-phenylsulfonamide derivatives was designed by starting from aniline, which is the simplest aromatic amine. These compounds were obtained in yields between 69 and 95%. Inhibitory properties of synthesized compounds on car

Palladium-catalyzed desulfitative arylation of sulfonamides with sodium arylsulfinates

A Pd(II)-catalyzed desulfitative arylation protocol between sulfonamides and sodium arylsulfinates was herein reported. The direct arylation reaction was successfully achieved by a Pd(II)/Ag(I)-mediated system without participation of any external ligands with a release of SO2. And different N-aryl sulfonamides were obtained readily in up to 86% yields, exhibiting good functional groups tolerance (25 examples).