39860-52-1

Basic information

• Product Name: 2-(benzoylsulfanyl)benzoic acid
• CAS NO: 39860-52-1
• Molecular Formula: C₁₄H₁₀O₃S
• Molecular Weight: 258.2924
• Mol File: 39860-52-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 410.8°C at 760 mmHg
• Flash Point: 202.2°C
• Density: 1.37g/cm³
• Vapor Pressure: 1.74E-07mmHg at 25°C
• Refractive Index: 1.671
• CAS DataBase Reference: 2-(benzoylsulfanyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(benzoylsulfanyl)benzoic acid(39860-52-1)
• EPA Substance Registry System: 2-(benzoylsulfanyl)benzoic acid(39860-52-1)

Safety Data

• Hazardous Substances Data: 39860-52-1(Hazardous Substances Data)

Usage

Structure

A derivative of benzoic acid with a thiol (sulfhydryl) group attached at the ortho position to the carboxylic acid group

Appearance

White crystalline solid

Molecular weight

274.292 g/mol

Reactivity

Used as a building block in the synthesis of various pharmaceuticals and organic compounds due to its reactivity

Biological activity

Potential antioxidant and anti-inflammatory properties

Applications

Potential applications in materials science and organic electronics due to its semiconducting properties

Upstream product

• 147-93-3 Thiosalicylic acid 
• 93-97-0 benzoic acid anhydride 
• 98-88-4 benzoyl chloride 

Downstream Products

• 784-62-3 1-thioflavone 
• 39860-53-2 Chlorure de benzoylthiosalicyloyle 
• 131747-12-1 2-(2-mercaptobenzoylamino)-6-hexanoylaminopyridine 
• 131747-09-6 1,3-bis<<<6-(2-mercaptobenzoylamino)pyrid-2-yl>amino>carbonyl>-5-(heptyloxy)benzene 
• 162968-35-6 1,3-bis<<<6-(2-(benzoylmercapto)benzoylamino)pyrid-2-yl>amino>carbonyl>-5-(heptyloxy)benzene 
• 162968-37-8 2-(2-(benzoylmercapto)benzoylamino)-6-hexanoylaminopyridine 
• 919103-49-4 thiobenzoic acid S-[2-(2,5-dimethyl-2H-pyrazol-3-ylcarbamoyl)-phenyl]ester 
• 1485-70-7 N-benzylbenzamide 
• 89928-06-3 methyl ester of 3-(N-benzoyl)aminopropionic acid 
• 405271-41-2 C₂₀H₂₄O₃SSi 

Relevant articles and documents

A bioluminescent probe for imaging endogenous hydrogen polysulfides in live cells and a murine model of bacterial infection

In this work, we report the first bioluminescent probe BP-PS for detecting H2Sn with high specificity and sensitivity. Owing to the bioluminescence imaging without requiring an excitation light source, tissue autofluorescence is eliminated and BP-PS shows a high signal-to-noise ratio. Moreover, BP-PS was successfully utilized to visualize endogenous H2Sn in live cells and a murine model of bacterial infection.

A one-pot preparation of N-2-mercaptobenzoyl-amino amides

The HIV-1 nucleocapsid (NCp7), structurally defined by zinc-binding domains, participates in crucial stages of the HIV-1 lifecycle and is mutationally nonpermissive, making it an attractive anti-HIV target. Mode of action studies have shown that the secondary structure and activity of NCp7 can be disrupted by acyl transfer from N-2-mercaptobenzoyl-amino amides. We have developed an improved one-pot reaction that affords N-2-mercaptobenzoyl-amino acids on multi-gram scales. This synthetic route allows for rapid modular construction and has greatly expanded the scope of easily accessible potential NCp7 inhibitors.

A new synthesis of 4H-1-benzothiopyran-4-ones using (trimethylsilyl)methylenetriphenylphosphorane

The reaction of silyl ester of S-acyl(aroyl) thiosalicylic acids 3 with (trimethylsilyl)methylenetriphenylphosphorane 4 in step wise fashion leads to the acylphosphoranes 7, which subsequently undergo intramolecular Wittig cyclization on the thiolester carbonyl to afford the 4H-1-benzothiopyran-4-ones 8 in good to excellent yields.