40350-84-3 Usage
Description
H-Hyp(Bzl)-OH · HCl is a chemical compound that consists of a hydroxyproline (Hyp) peptide with a benzyl (Bzl) group and a hydrochloride salt. The "H" in the name refers to the hydrogen atoms, "Hyp" stands for hydroxyproline, "Bzl" represents the benzyl group, and "OH" signifies the hydroxyl group. The presence of the hydrochloride salt indicates that the compound is in the form of a salt, with a chloride ion pairing with the positively charged part of the molecule. H-Hyp(Bzl)-OH · HCl is likely used in pharmaceutical and biochemical applications, as hydroxyproline is a crucial component of collagen and plays a role in various biological processes such as wound healing and connective tissue function. The benzyl group may also provide stability and aid in the molecule's solubility in organic solvents.
Uses
Used in Pharmaceutical Applications:
H-Hyp(Bzl)-OH · HCl is used as a pharmaceutical compound for its role in collagen synthesis and its potential involvement in wound healing and connective tissue function.
Used in Biochemical Research:
H-Hyp(Bzl)-OH · HCl is used as a biochemical research tool for studying the structure and function of collagen and other proteins containing hydroxyproline.
Used in Organic Synthesis:
H-Hyp(Bzl)-OH · HCl is used as a reagent in organic synthesis, where the benzyl group may provide stability and aid in the molecule's solubility in organic solvents.
Check Digit Verification of cas no
The CAS Registry Mumber 40350-84-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,3,5 and 0 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 40350-84:
(7*4)+(6*0)+(5*3)+(4*5)+(3*0)+(2*8)+(1*4)=83
83 % 10 = 3
So 40350-84-3 is a valid CAS Registry Number.
40350-84-3Relevant articles and documents
Dual stereocontrol in aldol reactions catalysed by hydroxyproline derivatives in the presence of a large amount of water
Gurka, András A.,Sz?ri, Kornél,Bartók, Mihály,London, Gábor
supporting information, p. 936 - 942 (2016/09/13)
Parameters influencing dual stereocontrol in aldol reactions of water miscible acetone with aromatic aldehydes in the presence of a large amount of water using hydroxyproline based catalysts were studied. Stereocontrol was achieved by changing the acidity and basicity of the reaction media by the addition of achiral salts in the presence of a single chiral catalyst. Under acidic conditions (NH4Cl salt) the (R)-aldol product was formed in excess while basic aqueous media (carboxylate salts) led to the enrichment of the (S)-enantiomer. Reaction conditions under which the reaction is feasible were optimised and the effect of the structure of the hydroxyproline-based catalysts was investigated. The results show that the formation of a biphasic micellar system and the presence of an appropriate catalyst are both crucial for the reaction to occur. Although the catalyst structure influenced the formation and stabilisation of the micellar system to a large extent, its effect on the enantioselectivities were found to be less pronounced.
Capped dipeptide phenethylamide inhibitors of the HCV NS3 protease
Nizi, Emanuela,Koch, Uwe,Ontoria, Jesus M.,Marchetti, Antonella,Narjes, Frank,Malancona, Savina,Matassa, Victor G.,Gardelli, Cristina
, p. 2151 - 2154 (2007/10/03)
The N-terminal aminoacid of phenethylamide tripeptide inhibitors of the hepatitis C virus NS3 protease can be replaced with an α-hydroxy acid to obtain more 'drug like' inhibitors with low micromolar activity. The preferred S-configuration of the capping