403793-16-8Relevant articles and documents
Synthesis of 3-arylpiperidines by a radical 1,4-aryl migration
Gheorghe, Alexandra,Quiclet-Sire, Beatrice,Vila, Xavier,Zard, Samir Z.
, p. 1653 - 1656 (2007/10/03)
(Chemical Equation Presented) A route to 3-arylpiperidines, 3-arylpyridines, and 5-arylpiperidin-2-ones involving a radical 1,4-aryl migration has been explored. The sequence requires a xanthate addition to an N-allylarylsulfonamide, followed by acetylation and treatment with dilauroyl peroxide to give the 1,4-aryl transfer product, which upon acidic hydrolysis affords the desired piperidine derivative.
Imidazolo-5-YL-2anilino-pyrimidines as agents for the inhibition of the cell proliffration
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Page/Page column 35, (2010/02/05)
Compounds of the formula (I): wherein R1, R2, R3, R4, R5, R6, p, q, and n are as defined within and a pharmaceutically acceptable salts and in vivo hydrolysable esters are described. Also described are processes for their preparation and their use as medicaments, particularly medicaments for producing a cell cycle inhibitory (anti-cell-proliferation) effect in a warm-blooded animal, such as man.