404-43-3 Usage
Description
N-(4-FLUOROPHENYL)-N'-METHYLTHIOUREA, also known as FLT, is a chemical compound with the molecular formula C8H8FN3S. It is a white crystalline solid that is sparingly soluble in water and soluble in organic solvents. FLT is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, as well as in the production of dyes and pigments. It is also used as a reagent for the determination of heavy metal ions in analytical chemistry.
Uses
Used in Pharmaceutical and Agrochemical Industries:
N-(4-FLUOROPHENYL)-N'-METHYLTHIOUREA is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals for its ability to contribute to the development of new and effective products.
Used in Dyes and Pigments Production:
N-(4-FLUOROPHENYL)-N'-METHYLTHIOUREA is used in the production of dyes and pigments due to its chemical properties that allow for the creation of a wide range of colors.
Used in Analytical Chemistry:
N-(4-FLUOROPHENYL)-N'-METHYLTHIOUREA is used as a reagent for the determination of heavy metal ions, providing a valuable tool for environmental and industrial testing.
Safety Precautions:
N-(4-FLUOROPHENYL)-N'-METHYLTHIOUREA is known to be a mild skin irritant and may cause eye irritation upon contact. It is important to handle and store this compound in a well-ventilated area and away from heat and open flame due to its flammability.
Check Digit Verification of cas no
The CAS Registry Mumber 404-43-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,0 and 4 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 404-43:
(5*4)+(4*0)+(3*4)+(2*4)+(1*3)=43
43 % 10 = 3
So 404-43-3 is a valid CAS Registry Number.
404-43-3Relevant articles and documents
Synthesis and biological evaluation of 3-benzyl-1-methyl- and 1-methyl-3-phenyl-isothioureas as potential inhibitors of iNOS
Paesano, Nicola,Marzocco, Stefania,Vicidomini, Caterina,Saturnino, Carmela,Autore, Giuseppina,De Martino, Giovanni,Sbardella, Gianluca
, p. 539 - 543 (2007/10/03)
Novel benzyl- and phenyl-isothioureidic derivatives have been synthesised and evaluated as inhibitors of nitric oxide synthesis, induced in lipopolysaccharide (LPS)-activated J774.A1 macrophage cell line. The most potent iNOS inhibitor resulting was 1-methyl-3-phenyl-S-methyl isothiourea 5l.
Guanidines
-
, (2008/06/13)
Novel substituted phenylquanidine compounds and processes for their preparation are disclosed. Their use as anti-hypertensive agents is also revealed.
