40641-92-7

Basic information

• Product Name: ethyl 2-(4-cyclopropylphenyl)acetate
• Synonyms: ethyl 2-(4-cyclopropylphenyl)acetate;Benzeneacetic acid, 4-cyclopropyl-, ethyl ester
• CAS NO: 40641-92-7
• Molecular Formula: C₁₃H₁₆O₂
• Molecular Weight: 204.26494
• Mol File: 40641-92-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 2-(4-cyclopropylphenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(4-cyclopropylphenyl)acetate(40641-92-7)
• EPA Substance Registry System: ethyl 2-(4-cyclopropylphenyl)acetate(40641-92-7)

Safety Data

• Hazardous Substances Data: 40641-92-7(Hazardous Substances Data)

Upstream product

• 14062-25-0 Ethyl 4-bromophenylacetate 
• 411235-57-9 cyclopropylboronic acid 
• 2622-14-2 tricyclohexylphosphine 
• 623-73-4 diazoacetic acid ethyl ester 
• 873-49-4 cyclopropylbenzene 

Downstream Products

• 40641-90-5 2-(4-cyclopropylphenyl)acetic acid 

Relevant articles and documents

USE OF T-TYPE CALCIUM CHANNEL BLOCKER FOR TREATING PRURITUS

A medicament for treating or preventing pruritus is provided. For the medicament for treating or preventing pruritus, a compound having a blocking action on Cav3.2T-type calcium channels represented by General Formulas (I) to (VI), a tautomer of the compo

Iron and manganese catalysts for the selective functionalization of arene C(sp2)-H bonds by carbene insertion

The first examples of the direct functionalization of non-activated aryl sp2 C-H bonds with ethyl diazoacetate (N2CHCO2Et) catalyzed by Mn- or Fe-based complexes in a completely selective manner are reported, with no formation of the frequently observed cycloheptatriene derivatives through competing Buchner reaction. The best catalysts are FeII or MnII complexes bearing the tetradentate pytacn ligand (pytacn= 1-(2-pyridylmethyl)-4,7-dimethyl-1,4,7-triazacyclononane). When using alkylbenzenes, the alkylic C(sp3)-H bonds of the substituents remained unmodified, thus the reaction being also selective toward functionalization of sp2 C-H bonds. Exclusive catalysis: Iron- and-manganese-based catalysts selectively functionalize the C(sp2)-H bonds of benzene or alkylbenzenes through the formal insertion of the CHCO2Et group from N2CHCO2Et (see scheme). When using alkylbenzenes, the alkylic C(sp3)-H bonds of the substituents remain unmodified.

PYRIDYL AMIDE T-TYPE CALCIUM CHANNEL ANTAGONISTS

The present invention is directed to pyridyl amide compounds which are antagonists of T-type calcium channels, and which are useful in the treatment or prevention of disorders and diseases in which T-type calcium channels are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which T-type calcium channels are involved.