40651-89-6

Basic information

• Product Name: 2-aminobutanenitrile
• Synonyms: 2-aminobutanenitrile;2-Aminobutyronitrile;2-AMINOBUTANENITRILE HCL
• CAS NO: 40651-89-6
• Molecular Formula: C₄H₈N₂
• Molecular Weight: 84
• Mol File: 40651-89-6.mol
• Article Data: 14

Chemical Properties

• Melting Point: 143-145 °C
• Boiling Point: 50 °C(Press: 3 Torr)
• Appearance: /
• Density: 0.914±0.06 g/cm3(Predicted)
• PKA: 5.92±0.29(Predicted)
• CAS DataBase Reference: 2-aminobutanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-aminobutanenitrile(40651-89-6)
• EPA Substance Registry System: 2-aminobutanenitrile(40651-89-6)

Safety Data

• Hazardous Substances Data: 40651-89-6(Hazardous Substances Data)

Usage

Description

2-aminobutanenitrile, also known as 2-butylamine, is a chemical compound with the molecular formula C4H9N. It is a colorless liquid with a faint amine odor and is commonly used in organic synthesis and pharmaceutical research. 2-aminobutanenitrile is highly reactive and can undergo various chemical reactions to form a variety of other compounds.

Uses

Used in Organic Synthesis:
2-aminobutanenitrile is used as a building block for the synthesis of various organic compounds due to its reactivity and ability to undergo different chemical reactions.
Used in Pharmaceutical Research:
2-aminobutanenitrile is used as an intermediate in the development of new pharmaceuticals, contributing to the creation of innovative drugs and therapies.
Used in Agricultural Chemicals Production:
2-aminobutanenitrile is used as a raw material in the production of agricultural chemicals, helping to develop effective solutions for crop protection and pest control.
Used in Pharmaceutical Production:
2-aminobutanenitrile is used as a key component in the manufacturing process of certain pharmaceuticals, playing a crucial role in the development of life-saving medications.
Used in Rubber Chemicals Production:
2-aminobutanenitrile is used in the production of rubber chemicals, which are essential for enhancing the properties and performance of rubber products.

Upstream product

• 4476-02-2 2-hydroxybutanenitrile 
• 64-17-5 ethanol 
• 74-90-8 hydrogen cyanide 
• 123-38-6 propionaldehyde 
• 773837-37-9 sodium cyanide 
• 123-75-1 pyrrolidine 
• 110-61-2 butanedinitrile 
• 32754-99-7 4-aminobutyronitrile 
• 4786-20-3 but-2-enenitrile 
• 544-92-3 copper(I) cyanide 
• 143-33-9 sodium cyanide 
• 151-50-8 potassium cyanide 

Downstream Products

• 4753-69-9 propan-1-imine 
• 89603-48-5 2-amino butyramide hydrochloride 
• 59133-38-9 4-Acetyl-3-amino-2-ethyl-5-methylpyrrole hydrochloride 
• 1096698-60-0 2-(2-oxo-1-pyrrolidinyl)butanenitrile 
• 7324-11-0 (S)-2-amino-butanamide 
• 1386992-24-0 (±)-2‐((benzylidene)amino)butanamide 
• 1492-24-6 L-2-aminobutyric acid 
• 53726-14-0 DL-2-aminobutanamide 
• 99841-23-3 N-(α-cyanopropyl)-p-toluenesulfonamide 
• 4426-48-6 1,2-butanediamine 
• 857980-07-5 4-ethyl-5-imino-thiazolidin-2-one 

Relevant articles and documents

Preparation method of aminobutyronitrile

The invention discloses a preparation method of aminobutyronitrile, which comprises the following steps: mixing ammonia water with ammonium bicarbonate and methyl isobutyl ketone, adding sodium cyanide, dropwisely adding n-propionaldehyde, carrying out heat preservation reaction, conducting standing for stratification after the reaction is finished, and concentrating the organic phase to remove the solvent, thereby obtaining aminobutyronitrile. According to the method, the raw materials are easy to obtain, the reaction conditions are environmentally friendly and safe, the reaction time is short, the solvent can be recycled, the steps are simple, and the obtained product has high purity.

Method for preparing 2-aminobutyronitrile through microchannel reactor

The invention provides a method for preparing 2-aminobutyronitrile through a microchannel reactor. The method includes: with a NaCN/ammonia/NH4Cl/water mixed solution as a first material and n-propanal as a second material, feeding the raw materials into the microchannel reactor, and performing continuous flow synthesis at 10-40 DEG C to prepare the 2-aminobutyronitrile, reaction time being 5-40 sand pressure being 0-15 bar. Compared with a common kettle reactor in the prior art, the method is short in reaction time, is low in liquid holdup volume, is low in impurity and high in yield, is free of amplification effect, is greatly improved in safety and controllability than the kettle reactor, is beneficial to continuous automatic control, and improves production efficiency.

Preparation method and preparation system of 2-aminobutyramide

The invention provides a preparation method and a preparation system of 2-aminobutyramide. The preparation method comprises: (1) generating 2-hydroxybutyronitrile from hydrogen cyanide and n-propanalunder the action of a first catalyst; (2) adding an ammonia source and a second catalyst to the 2-hydroxybutyronitrile obtained in the step (1), and carrying out a reaction to generate 2-aminobutyronitrile; and (3) removing the excess ammonia from the reaction solution obtained in the step (2), adding a strong base and a third catalyst, and carrying out a hydrolysis reaction to obtain DL-2-aminobutanamide. According to the present invention, with the method and the system, the wastewater, the waste gas and the waste residue can be effectively reduced, the consumption of hydrogen cyanide can beeffectively reduced, the content of the target product can be increased, and the production cost can be reduced.