4121-40-8 Usage
Description
Tenofovir Disoproxil Related Compound B (10 mg) ((E)-9-(Prop-1-enyl)-9H-purin-6-amine) is an N-substituted purine derivative and an impurity associated with Tenofovir (T018500). It is a white to pale yellow solid and is known for its pharmaceutical relevance.
Uses
Used in Pharmaceutical Industry:
Tenofovir Disoproxil Related Compound B (10 mg) ((E)-9-(Prop-1-enyl)-9H-purin-6-amine) is used as an impurity reference for the development and quality control of Tenofovir, an antiviral medication. Its presence is crucial for ensuring the purity and efficacy of the final drug product, as it helps in monitoring and controlling the synthesis process of Tenofovir.
Used in Research and Development:
In the field of research and development, Tenofovir Disoproxil Related Compound B (10 mg) ((E)-9-(Prop-1-enyl)-9H-purin-6-amine) serves as a valuable compound for studying the properties and behavior of N-substituted purines. This can lead to advancements in the understanding of their potential applications in medicinal chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 4121-40-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,2 and 1 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 4121-40:
(6*4)+(5*1)+(4*2)+(3*1)+(2*4)+(1*0)=48
48 % 10 = 8
So 4121-40-8 is a valid CAS Registry Number.
4121-40-8Relevant articles and documents
A method of synthesis for fuwei intermediates (by machine translation)
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, (2017/08/28)
The invention discloses a method for synthesizing for fuwei intermediate of the method, the method comprises: formula 2 compound of formula 9 - propenyl adenine as raw materials, in the (S)- (-) - 2, 2 '- double (b benzene phosphine base) - 1, 1' - binaphthyl induction, and tetramethyl piperidine nitrogen oxide oxidation reaction to obtain the type 1 indicated by the tenofovir intermediate (R)- 9 - (2 - hydroxy-propyl) adenine; Through the method of the invention for the preparation of tenofovir intermediate (R)- 9 - (2 - hydroxy-propyl) adenine, mild reaction conditions, the industrial application and popularization; yield of the object product, good selectivity; without using a large amount of chiral compounds, the use of a small amount of chiral auxiliary can be induced oxidation, the cost is low. (by machine translation)