4126-60-7

Basic information

• Product Name: 3-(Benzyloxy)propionic acid methyl ester
• Synonyms: 3-(Benzyloxy)propionic acid methyl ester;3-Benzyloxypropionic acid methyl ester
• CAS NO: 4126-60-7
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.2271
• Mol File: 4126-60-7.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 284.2°Cat760mmHg
• Flash Point: 98.6°C
• Appearance: /
• Density: 1.069g/cm³
• Vapor Pressure: 0.00302mmHg at 25°C
• Refractive Index: 1.497
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-(Benzyloxy)propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(Benzyloxy)propionic acid methyl ester(4126-60-7)
• EPA Substance Registry System: 3-(Benzyloxy)propionic acid methyl ester(4126-60-7)

Safety Data

• Hazardous Substances Data: 4126-60-7(Hazardous Substances Data)

Usage

General Description

"3-(Benzyloxy)propionic acid methyl ester" is a chemical compound with the molecular formula C12H14O3. It is an ester derived from 3-(Benzyloxy)propionic acid, which is commonly used in the synthesis of pharmaceuticals and agrochemicals. 3-(Benzyloxy)propionic acid methyl ester possesses potential pharmacological activity and is used in the field of medicinal chemistry for drug discovery. It is known for its role as a building block in organic synthesis and may have applications in the development of new drugs or biologically active molecules. Additionally, it is important to handle this compound with care, as it may pose health hazards if not used properly.

InChI:InChI=1/C11H14O3/c1-13-11(12)7-8-14-9-10-5-3-2-4-6-10/h2-6H,7-9H2,1H3

Upstream product

• 67-56-1 methanol 
• 6328-48-9 3-benzyloxypropionitrile 
• 4799-68-2 3-benzyloxypropan-1-ol 
• 4039-82-1 Benzyl propargyl ether 
• 100-51-6 benzyl alcohol 
• 292638-85-8 acrylic acid methyl ester 
• 186581-53-3 diazomethane 
• 100-39-0 benzyl bromide 
• 865-33-8 potassium methanolate 
• 1160845-83-9 C₁₁H₁₄N₂O₃ 

Downstream Products

• 93652-31-4 3-Benzyloxy-propionsaeure-benzylester 
• 106296-40-6 (2S,3S,4S)-4-Benzyloxy-2-benzyloxymethyl-3-hydroxy-pentanoic acid methyl ester 
• 106296-41-7 (2R,3S,4S)-4-Benzyloxy-2-benzyloxymethyl-3-hydroxy-pentanoic acid methyl ester 
• 1315607-28-3 3-{2-[(phenylmethyl)oxy]ethyl}-1H-1,2,4-triazol-5-amine 
• 1315607-44-3 7-chloro-5-methyl-2-{2-[(phenylmethyl)oxy]ethyl}[1,2,4]triazolo[1,5-a]pyrimidine 
• 1315607-36-3 5-methyl-2-{2-[(phenylmethyl)oxy]ethyl}[1,2,4]triazolo[1,5-a]pyrimidin-7-ol 
• 1315607-26-1 5-methyl-2-{2-[((phenylmethyl)methyl)oxy]ethyl}-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine 
• 163812-44-0 4-benzyloxy-1-dimethylphosphinoylbutan-2-one 
• 141805-88-1 (4R)-3-<(2S,3R)-3-<(tert-Butyldimethylsilyl)oxy>-2-<(benzyloxy)methyl>butanoyl>-4-isopropyl-1,3-thiazolidine-2-thione 
• 141805-89-2 (2S,3R)-3-<(tert-Butyldimethylsilyl)oxy>-2-<(benzyloxy)methyl>-N-(4-methoxyphenyl)butylamide 
• 141805-87-0 (4R)-3-<(2S,3R)-3-Hydroxy-2-<(benzyloxy)methyl>butanoyl>-4-isopropyl-1,3-thiazolidine-2-thione 
• 141805-86-9 (4R)-3-<3-(Benzyloxy)propanoyl>-4-isopropyl-1,3-thiazolidine-2-thione 
• 119027-80-4 L-β-benzyloxypropionyl-carbobenzoxyornithine benzyl ester 
• 119027-80-4 5-Benzyloxycarbonylamino-2-(3-benzyloxy-propionylamino)-pentanoic acid benzyl ester 

Relevant articles and documents

Conversion of alcohols to alkyl esters and carboxylic acids using heterogeneous palladium-based catalysts

Disclosed are methods for synthesizing an ester or a carboxylic acid from an organic alcohol. To form the ester one reacts, in the presence of oxygen gas, the alcohol with methanol or ethanol. This reaction occurs in the presence of a catalyst comprising palladium and a co-catalyst comprising bismuth, tellurium, lead, cerium, titanium, zinc and/or niobium (most preferably at least bismuth and tellurium). Alternatively that catalyst can be used to generate an acid from that alcohol, when water is also added to the reaction mix.

Rhodium-catalyzed oxygenative addition to terminal alkynes for the synthesis of esters, amides, and carboxylic acids

A gem of a couple: The title reaction of terminal alkynes with O and Nnucleophiles proceeds in the presence of [Rh(cod)Cl}2], P(4-FC 6H4)3, and 4-picoline N-oxide. Alcohols, amines, and water add to the terminal alkynes to give esters, amides, and carboxylic acids, respectively. The reaction involves formation of a rhodium vinylidene, oxidation to a ketene by oxygen transfer, and nucleophilic addition.

Pyrazole derivatives

This invention relates to pyrazole derivatives of formula (I) or pharmaceutically acceptable salts, solvates or derivative thereof, wherein R1 to R4 are defined in the description, and to processes for the preparation thereof, intermediates used in their preparation of, compositions containing them and the uses of such derivatives. The compounds of the present invention bind to the enzyme reverse transcriptase and are modulators, especially inhibitors thereof. As such the compounds of the present invention are useful in the treatment of a variety of disorders including those in which the inhibition of reverse transcriptase is implicated. Disorders of interest include those caused by Human Immunodificiency Virus (HIV) and genetically related retroviruses, such as Acquired Immune Deficiency Syndrome (AIDS).