41335-47-1Relevant articles and documents
A novel library of saccharin and acesulfame derivatives as potent and selective inhibitors of carbonic anhydrase IX and XII isoforms
Carradori, Simone,Secci, Daniela,De Monte, Celeste,Mollica, Adriano,Ceruso, Mariangela,Akdemir, Atilla,Sobolev, Anatoly P.,Codispoti, Rossella,De Cosmi, Federica,Guglielmi, Paolo,Supuran, Claudiu T.
, p. 1095 - 1105 (2016)
Small libraries of N-substituted saccharin and N-/O-substituted acesulfame derivatives were synthesized and tested as atypical and selective inhibitors of four different isoforms of human carbonic anhydrase (hCA I, II, IX and XII, EC 4.2.1.1). Most of the
Metal-free, highly efficient organocatalytic amination of benzylic C-H bonds
Xue, Qicai,Xie, Jin,Li, Huamin,Cheng, Yixiang,Zhu, Chengjian
supporting information, p. 3700 - 3702 (2013/05/09)
A new synthetic approach toward direct C-N bond formation through sp 3 C-H activation has been developed under metal-free conditions. Both primary and secondary benzylic C-H substrates could react smoothly with various amines to give only mono-amination products with good to excellent yields. The Royal Society of Chemistry 2013.