41632-04-6

Basic information

• Product Name: 2-Amino-6-chlorobenzoic acid methyl ester
• Synonyms: 2-Amino-6-chlorobenzoic acid methyl ester;Methyl 2-aMino-6-chlorobenzoate;2-AMino-6-chlorbenzoicacidMethyl ester;6-Chloroanthranilic acid methyl ester;Methyl 6-chloroanthranilate
• CAS NO: 41632-04-6
• Molecular Formula: C₈H₈ClNO₂
• Molecular Weight: 185.61
• Mol File: 41632-04-6.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 290.4±20.0 °C(Predicted)
• Appearance: /
• Density: 1.311±0.06 g/cm3(Predicted)
• PKA: 1.14±0.10(Predicted)
• CAS DataBase Reference: 2-Amino-6-chlorobenzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-6-chlorobenzoic acid methyl ester(41632-04-6)
• EPA Substance Registry System: 2-Amino-6-chlorobenzoic acid methyl ester(41632-04-6)

Safety Data

• Hazardous Substances Data: 41632-04-6(Hazardous Substances Data)

Usage

General Description

2-Amino-6-chlorobenzoic acid methyl ester, also known as 6-Chloro-anthranilic acid methyl ester or 6-Chloro-2-aminobenzoic acid methyl ester, is a chemical compound with the molecular formula C8H8ClNO2. It is a methyl ester derivative of 2-amino-6-chlorobenzoic acid and is used in various chemical reactions and organic synthesis. It is an important intermediate in the production of pharmaceuticals, agrochemicals, and other organic compounds. 2-Amino-6-chlorobenzoic acid methyl ester is typically used in the production of specialty chemicals, pharmaceuticals, and as a research reagent in various laboratory settings. It has potential applications in drug development, agrochemicals, and other industrial uses due to its unique chemical properties.

Upstream product

• 4743-17-3 5-Chloroisatoic anhydride 
• 63497-60-9 8-chloro-2H-benzo[d][1,3]oxazine-2,4(1H)-dione 
• 77820-58-7 methyl 3-chloroanthranilate 
• 20829-96-3 5-chloro-1H-benzo[d][1,3]oxazine-2,4-dione 
• 616-38-6 carbonic acid dimethyl ester 
• 2148-56-3 2-chloro-6-aminobenzoic acid 
• 77-78-1 dimethyl sulfate 
• 80563-87-7 2-chloro-6-nitro-benzoic acid methyl ester 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 74-88-4 methyl iodide 
• 5344-49-0 2-chloro-6-nitrobenzoic acid 
• 6575-07-1 2-chloro-6-nitrobenzonitrile 
• 19407-42-2 2-(acetylamino)-6-chlorobenzoic acid 
• 87-60-5 3-chloro-2-methylbenzenamine 

Downstream Products

• 57334-24-4 2-Chloro-6-isobutyrylamino-benzoic acid methyl ester 
• 874472-81-8 2-(2-amino-6-chlorophenyl)propan-2-ol 
• 58331-95-6 6-chloro-2-cyanobenzoic acid methyl ester 
• 50440-85-2 2-amino-5-chloroquinazolin-4-ol 
• 943138-46-3 6-amino-3-bromo-2-chlorobenzoic acid methyl ester 

Relevant articles and documents

Compound for inhibiting IDO and application of compound

The invention discloses a compound for inhibiting IDO and application of the compound, in particular to application of a compound shown in formula I, or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, or a solvate thereof, or a prod

IMIDAZOPIPERAZINE INHIBITORS OF TRANSCRIPTION ACTIVATING PROTEINS

The present disclosure relates to heterocyclic compounds and methods which may be useful as inhibitors of transcription activating proteins such as CBP and P300 for the treatment or prevention of diseases such as proliferative diseases, inflammatory disorders, autoimmune diseases, and fibrotic diseases.

Iodine(III) Reagent-Mediated Intramolecular Amination of 2-Alkenylanilines to Prepare Indoles

A variety of 3-substituted and 2,3-disubstituted indoles were synthesized efficiently in good yields through the intramolecular amination of 2-alkenylanilines promoted by readily available iodine(III) reagents in a short reaction time. Mechanistic studies showed that the reaction pathway went through a nitrenium ion and that 3-acetoxy indoline was the key intermediate in the indole formation. The indole product was easily prepared on a gram scale and amination also proceeded smoothly using catalytic 3,5-dimethylphenyl iodine in the presence of mCPBA. Furthermore, the indolo[3,2-a]carbazole scaffold was prepared in good yield in six steps from commercial ortho-iodoaniline. (Figure presented.).