4224-96-8 Usage
Description
1-(4-METHYLPHENYL)-3-PHENYLPROP-2-EN-1-ONE, also known as 4-Methyl-4'-hydroxychalcone, is a chemical compound with a molecular formula C16H14O. It is a yellow crystalline solid that is commonly used as an intermediate for the synthesis of various pharmaceuticals and organic chemicals. 1-(4-METHYLPHENYL)-3-PHENYLPROP-2-EN-1-ONE has been found to exhibit various pharmacological activities, including antioxidant, anti-inflammatory, and anti-cancer properties. It has also been studied for its potential to be used in the treatment of neurodegenerative diseases.
Uses
Used in Pharmaceutical Industry:
1-(4-METHYLPHENYL)-3-PHENYLPROP-2-EN-1-ONE is used as an intermediate for the synthesis of various pharmaceuticals and organic chemicals. Its pharmacological activities, such as antioxidant, anti-inflammatory, and anti-cancer properties, make it a valuable compound in the development of new drugs.
Used in Neurodegenerative Disease Treatment:
1-(4-METHYLPHENYL)-3-PHENYLPROP-2-EN-1-ONE is used as a potential treatment for neurodegenerative diseases due to its pharmacological properties. Its antioxidant and anti-inflammatory activities may contribute to the prevention or treatment of these conditions.
Used in Production of Natural Products:
1-(4-METHYLPHENYL)-3-PHENYLPROP-2-EN-1-ONE is used in the production of natural products, including essential oils and food flavorings. Its unique chemical structure and properties make it a valuable component in creating various natural products for different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 4224-96-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,2 and 4 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4224-96:
(6*4)+(5*2)+(4*2)+(3*4)+(2*9)+(1*6)=78
78 % 10 = 8
So 4224-96-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H14O/c1-13-7-10-15(11-8-13)16(17)12-9-14-5-3-2-4-6-14/h2-12H,1H3
4224-96-8Relevant articles and documents
Palladium-Catalyzed Synthesis of α-Methyl Ketones from Allylic Alcohols and Methanol
Biswal, Priyabrata,Samser, Shaikh,Meher, Sushanta Kumar,Chandrasekhar, Vadapalli,Venkatasubbaiah, Krishnan
supporting information, p. 413 - 419 (2021/11/01)
One-pot synthesis of α-methyl ketones starting from 1,3-diaryl propenols or 1-aryl propenols and methanol as a C1 source is demonstrated. This one-pot isomerization-methylation is catalyzed by commercially available Pd(OAc)2 with H2O as the only by-product. Mechanistic studies and deuterium labelling experiments indicate the involvement of isomerization of allyl alcohol followed by methylation through a hydrogen-borrowing pathway in these isomerization-methylation reactions.
Activated charcoal-mediated synthesis of chalcones catalyzed by NaOH in water
Tanemura, Kiyoshi,Rohand, Taoufik
supporting information, (2021/02/27)
A variety of chalcones were synthesized in good yields by the activated charcoal-mediated aldol reactions between benzaldehydes and acetophenones catalyzed by NaOH in water. 2,6-Bis((E)-benzylidene)cyclohexan-1-ones were prepared by the aldol reactions between benzaldehydes and cyclohexanone. Activated charcoal could be recycled five times without the significant decrease of yields.
New 2-Pyrazoline and Hydrazone Derivatives as Potent and Selective Monoamine Oxidase A Inhibitors
Salgin-Goksen, Umut,Telli, Gokcen,Erikci, Acelya,Dedecengiz, Ezgi,Tel, Banu Cahide,Kaynak, F. Betul,Yelekci, Kemal,Ucar, Gulberk,Gokhan-Kelekci, Nesrin
, p. 1989 - 2009 (2021/02/16)
Thirty compounds having 1-[2-(5-substituted-2-benzoxazolinone-3-yl) acetyl]-3,5-disubstitutedphenyl-2-pyrazoline structure and nine compounds having N′-(1,3-disubstitutedphenylallylidene)-2-(5-substituted-2-benzoxazolinone-3-yl)acetohydrazide skeleton wer